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Cholesterol Ester: Lysolecithin Acyltransferase Activity of the Aorta

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Atherosclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 82))

Abstract

Enzyme-catalyzed transfer from lecithin on cholesterol to form cholesterol ester and lysolecithin (LCAT+) 1/ in the arterial wall has been found (1) but not much is known about the reaction in reverse direction. It seemed to be of interest, therefore, to investigate the cholesterol ester: lysolecithin acy1 transfer activity (LCAT-) of the aortic wall, as compared with LCAT+ and cholesterol esterase activities.

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References

  1. Abdulla, Y.H., Orton, C.C. and Adams, C.W.M., Cholesterol esterification by transacylation in human and experimental atheromatous lesions, J. Atheroseler. Res., 8 (1968) 967.

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  2. Patelski, J., Pniewska, B., Pioruńska, M. and Obrebska, M., The arterial acyl-CoA: cholesterol acyltransferase and cholesterol ester hydrolase activities. In vitro effect of substrates with fatty acid of different chain length and saturation, Atherosclerosis, 22 (1975) 287–291.

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  3. Patelski, J. and Pioruńska, M., Cholesterol ester:lysolecithin transacylation in the aorta, to be published.

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  4. Patelski, J., Participation of phospholipids in arterial metabolism of cholesterol esters, in this book.

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© 1977 Plenum Press, New York

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Patelski, J., Pioruńska, M. (1977). Cholesterol Ester: Lysolecithin Acyltransferase Activity of the Aorta. In: Manning, G.W., Haust, M.D. (eds) Atherosclerosis. Advances in Experimental Medicine and Biology, vol 82. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4220-5_71

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  • DOI: https://doi.org/10.1007/978-1-4613-4220-5_71

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4222-9

  • Online ISBN: 978-1-4613-4220-5

  • eBook Packages: Springer Book Archive

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