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Inhibition of Platelet Adherence to Damaged Vessel wall by Drugs

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 82))

Abstract

Adherence of platelets to subendothelial structures of damaged vessel walls is involved in several aspects of vascular disease; (a) the adherence of platelets to the vessel wall leads to the development of arterial thrombi and thromboembolic complications of atherosclerosis; (b) platelets release a factor which promotes the growth of smooth muscle cells (1) and fibroblasts (2) and thus could be involved in the development of atherosclerotic lesions; (c) platelets also release or form elastase (3), collagenase (4) and materials which increase vascular permeability (5).

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References

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© 1977 Plenum Press, New York

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Cazenave, JP., Guccione, M.A., Packham, M.A., Mustard, J.F. (1977). Inhibition of Platelet Adherence to Damaged Vessel wall by Drugs. In: Manning, G.W., Haust, M.D. (eds) Atherosclerosis. Advances in Experimental Medicine and Biology, vol 82. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4220-5_47

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  • DOI: https://doi.org/10.1007/978-1-4613-4220-5_47

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4222-9

  • Online ISBN: 978-1-4613-4220-5

  • eBook Packages: Springer Book Archive

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