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Studies on the Role of Increased Arterial Glycolysis in Atherogenesis

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Atherosclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 82))

Abstract

Aerobic glycolysis is a comparative rarity in normal tissues, whereas it is almost the hallmark of neoplastic tissue (1), and it also appears to be a characteristic of arterial metabolism. The question arises whether the high rate of arterial glycolysis is in any way related to atherogenesis. The conclusions from different lines of investigations appear to shed some light in this regard.

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References

  1. Gregg, C.T. (1972). Some aspects of the energy metabolism of mammalian cells. In “Growth, Nutrition, and Metabolism of Cells in Culture”, G. H. Rothblat and V. J. Cristofalo, (Eds.), Academic Press, New York and London, Vol. I, p.83.

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  2. Zemplenyi, T., and Rosenstein, A. J. (1975). Arterial enzymes and their relation to atherosclerosis in pigeons. Exp. Mol. Pathol. 22, 225.

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  4. Zemplenyi, T. (1975). Vascular Metabolism, Vascular Enzymes, and the Effect of Drugs. In “Pharmacology of Hypolipidemic Agents”, Handbook of Exp. Pharmacology, Springer-Verlag, Berlin, Heidelberg, New York, Vol. 41.

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  5. Benditt, E. P. and Benditt, J. M. (1973). Evidence for a monoclonal origin of human atherosclerotic plaques. Proc. Nat. Acad. Sci. U.S.A. 70, 1753.

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Author information

Authors and Affiliations

  1. USC School of Medicine, Los Angeles, CA, USA

    T. Zemplenyi, D. H. Blankenhorn, A. J. Rosenstein & N. Alexander

Authors
  1. T. Zemplenyi
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  2. D. H. Blankenhorn
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  3. A. J. Rosenstein
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  4. N. Alexander
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Editor information

Editors and Affiliations

  1. University of Western Ontario, London, Ontario, Canada

    George W. Manning  & M. Daria Haust  & 

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© 1977 Plenum Press, New York

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Zemplenyi, T., Blankenhorn, D.H., Rosenstein, A.J., Alexander, N. (1977). Studies on the Role of Increased Arterial Glycolysis in Atherogenesis. In: Manning, G.W., Haust, M.D. (eds) Atherosclerosis. Advances in Experimental Medicine and Biology, vol 82. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4220-5_28

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  • DOI: https://doi.org/10.1007/978-1-4613-4220-5_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4222-9

  • Online ISBN: 978-1-4613-4220-5

  • eBook Packages: Springer Book Archive

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