Abstract
The triglyceride-rich lipoproteins, chylomicrons and very low density lipoproteins, are initially catabolised by enzymatic removal of part of their triglyceride mass in extrahepatic tissues (1). Subsequently the cholesteryl esters and part of the cholesterol retained in the chylomicron remnant particles are cleared from plasma by liver; in the hepatectomised rat chylomicron triglyceride is cleared but chylomicron cholesterol and cholesteryl esters accumulate in plasma in particles with an apparent mean diameter approximately half that of their precursor chylomicrons (2).
This work was supported by M.R.C. Operating Grant #MA-3900.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
HAVEL, R. J. In Handbook of Physiology, Section 5, American Physiological Society, Washington D.C., 499–507 (1965).
REDGRAVE, T. G., J. Clin. Invest. 49, 465–471 (1970).
RUDEL, L. L., J. A. LEE, M. M. MORRIS and J. M. FELTS, Biochem. J. 139, 89–95 (1974).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1977 Plenum Press, New York
About this chapter
Cite this chapter
Vost, A., Pocock, D.ME., Pleet, S. (1977). Chylomicron Remnant Particle Formation In Vivo in Hepatectomised Rat. In: Manning, G.W., Haust, M.D. (eds) Atherosclerosis. Advances in Experimental Medicine and Biology, vol 82. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4220-5_20
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4220-5_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4222-9
Online ISBN: 978-1-4613-4220-5
eBook Packages: Springer Book Archive