The Action of 1αhydroxy Vitamin D3 and Phosphate Supplements in Hypophosphataemic Osteomalacia

  • M. Peacock
  • J. E. Aaron
  • P. J. Heyburn
  • B. E. C. Nordin
Part of the Advances in Experimental Medicine and Biology book series (AEMB)

Abstract

Vitamin D resistant hypophosphataemic osteomalacia (VDRHPO) occurs as an inherited disorder or more unusually in association with certain connective tissue tumours1. The primary defect is considered to be a failure of phosphate transport with decreased tubular phosphate reabsorption and hypophosphataemia resulting in osteomalacia and myopathy2.

Keywords

Phosphorus Magnesium Creatinine Proline Crest 

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References

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    WILLIAMS, T.F. and WINTERS, R.W. Familial (Hereditary) Vitamin D — Resistant Rickets with hypophosphatemia. In The Metabolic Basis of Inherited Disease. Ed. Stanbury, J.B. Wyngaarden, J.B. and Fredrickson, D.S., McCraw-Hill, New York, 1972.Google Scholar
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Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • M. Peacock
    • 1
  • J. E. Aaron
    • 1
  • P. J. Heyburn
    • 1
  • B. E. C. Nordin
    • 1
  1. 1.M.R.C. Mineral Metabolism UnitThe General InfirmaryLeeds, YorkshireEngland

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