Abstract
X-linked familial hypophosphatemia (XLH) is a hereditary disorder of phosphate metabolism. The marked reduction of renal tubular phosphate reabsorption is followed by chronic hypophosphatemia with rickets and growth retardation. The rickets are resistant to a normal dosage of vitamin D, but they can be healed or prevented by pharmacological doses of vitamin D. An additional oral phosphate substitution was shown by West (1) and Glorieux (2) to induce growth acceleration.
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© 1977 Springer Science+Business Media New York
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Krohn, P.H., Offermann, G., Brandis, M., Brodehl, J., Hanke, K., Offner, G. (1977). Occurrence of Hyperparathyroidism in Children with X-Linked Hypophosphatemia under Treatment with Vitamin D and Phosphate. In: Massry, S.G., Ritz, E. (eds) Phosphate Metabolism. Advances in Experimental Medicine and Biology, vol 81. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-4217-5_34
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DOI: https://doi.org/10.1007/978-1-4613-4217-5_34
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