The Postproximal Site of Phosphate Reabsorption in Presence and Absence of Parathyroid Hormone

  • R. Greger
  • F. Lang
  • G. Marchand
  • F. G. Knox
Part of the Advances in Experimental Medicine and Biology book series (AEMB)


From previous studies there is ample evidence that phosphate, in addition to its proximal reabsorption is reabsorbed at some postproximal site (1–3,5,6,8,9,11). In free flow micropuncture studies this reabsorption has at least partially been ascribed to the distal tubule and collecting duct system (1,5). In microinjection studies, on the other hand, no reabsorption of phosphate beyond the loop of Henle could be detected (4,10). These data, however, are methodologically not unequivocal since the phosphate load injected exceeded the amount of phosphate which ought to be expected there under conditions of free flowing tubular fluid. The free flow micropuncture data also are subject to restricted interpretation since it seems likely that nephron heterogeneity in regard to phosphate reabsorption exists between superficial cortical and deeper nephrons.


Proximal Tubule Distal Convoluted Tubule Phosphate Reabsorption Phosphate Load Micropuncture Study 
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Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • R. Greger
    • 1
  • F. Lang
    • 1
  • G. Marchand
    • 1
  • F. G. Knox
    • 1
  1. 1.Dept. of Physiology & BiophysicsMayo FoundationRochesterUSA

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