Abstract
Although phosphaturia is the most characteristic renal effect of parathyroid hormone, PTH may also affect the renal handling of sodium, bicarbonate, calcium, glucose and amino acids (1). The relationship between these changes and the alterations in phosphate transport is unclear but information on this point may be useful in determining the mechanisms whereby PTH affects such a broad range of renal function.
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References
Aurbach, G.D., and Heath, D. A.: Parathyroid hormone and calcitonin regulation of renal function. Kidney Internat. 6: 331, 1974.
Dennis, V.W., Woodhall, P.B., and Robinson, R.R.: Characteristics of phosphate transport in the isolated proximal tubule. Am. J. Physiol. 231:979, 1976
Dennis, V.W., Bello-Reuss, E., and Robinson, R.R.: Responsiveness of phosphate transport to parathyroid hormone in three segments of the rabbit nephron. (Submitted for publication)
Agus, Z.S., Gardner, L.B., Beck, L. H., and Goldberg, M.: Effects of parathyroid hormone on renal tubular reabsorption of calcium, sodium, and phosphate. Am. J. Physiol. 224: 1143, 1973.
Schneider, E.G.: Effect of parathyroid hormone secretion on sodium reabsorption by the proximal tubule. Am. J. Physiol. 229: 1170, 1975.
Burg, M., Grantham, J., Abramow, M., and Orloff, J.: Preparation and study of fragments of single rabbit nephrons. Am. J. Physiol. 210: 1293, 1966.
Dennis, V. W.: Influence of bicarbonate on parathyroid hormone-induced changes in fluid absorption by the proximal tubule. Kidney Internat. 10:373, 1976.
Cardinal, J., Lutz, M.D., Burg, M.B., and Orloff, J.: Lack of relationship of potential difference to fluid absorption in the proximal renal tubule. Kidney Internat. 7: 94, 1975.
Ramsay, J.A., Brown, R.H.J., and Croghan, P.C.: Electrometric titration of chloride in small volumes. J. Exp. Biol. 32: 822, 1955.
Amiel, C., Kuntziger, H., and Richet, G.: Micropuncture study of handling of phosphate by proximal and distal nephron in normal and parathyroidectomized rat. Evidence for distal reabsorption. Pfluegers Arch. 317: 93, 1970.
Hellman, D.E., Au, W.Y.M., Bartter, F.C.: Evidence for a direct effect of parathyroid hormone on urinary acidification. Am. J. Physiol. 209: 643, 1965.
Barratt, L., Rector, F.C., Kokko, J.P., and Seldin, D.W.: Factors governing the transepithelial potential difference across the proximal tubule of the rat kidney. J. Clin. Invest. 53: 454, 1974.
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Dennis, V.W. (1977). Parathyroid Hormone-Induced Inhibition of Bicarbonate-Dependent Fluid Absorption in the Proximal Renal Tubule of the Rabbit. In: Massry, S.G., Ritz, E. (eds) Phosphate Metabolism. Advances in Experimental Medicine and Biology, vol 81. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-4217-5_13
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DOI: https://doi.org/10.1007/978-1-4613-4217-5_13
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