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Animal Behavioral Models of Relevance to Psychiatry

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Handbook of Psychopharmacology

Abstract

Tests of the behavior of laboratory animals are widely used for evaluating psychotropic drugs, but the interpretation of behavioral changes and the process of extrapolation to man continue to pose considerable problems. It is far easier to evaluate drugs that act primarily on “physical” systems; cardiovascular or respiratory effects, antibiotic or antiinflammatory actions lend themselves more readily to comparative assessments. Measures and responses can be specified with greater precision, and it is also possible to give roughly equal weightings to the information that is obtained from different species, including man (White et al., 1973).

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Authors and Affiliations

  1. Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, England

    R. Kumar

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  1. Department of Pharmacology, University of Cambridge, USA

    Leslie L. Iversen

  2. Department of Psychology, University of Cambridge, USA

    Susan D. Iversen

  3. Departments of Pharmacology and Psychiatry, The Johns Hopkins University School of Medicine, USA

    Solomon H. Snyder

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© 1977 Plenum Press, New York

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Kumar, R. (1977). Animal Behavioral Models of Relevance to Psychiatry. In: Iversen, L.L., Iversen, S.D., Snyder, S.H. (eds) Handbook of Psychopharmacology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4214-4_8

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