The Contribution of Ethological Techniques to the Study of Drug Effects

  • J. H. Mackintosh
  • M. R. A. Chance
  • A. P. Silverman

Abstract

Centrally acting drugs, by definition, influence the function of the nervous system and therefore inevitably affect behavior, and indeed the desired effect of such drugs is, in general, alteration of behavior. In addition, many other drugs may have behavioral side effects, and a variety of adventitious substances such as solvents and pesticides have also been reported to modify the actions and outlook of those encountering them. Investigation of the action of these agents therefore includes the need to measure behavioral change. This measuring must be done both qualitatively, so that the type of behavior influenced can be recognized, and quantitatively, so that the magnitude of the effect can be estimated. The success of any procedure that is to evaluate the behavioral effects of a drug therefore depends on the ability of the procedure to discriminate among different types of behavior and on its susceptibility to accurate measurement.

Keywords

Cage Nicotine Morphine Testosterone Beach 

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • J. H. Mackintosh
    • 1
  • M. R. A. Chance
    • 1
  • A. P. Silverman
    • 2
  1. 1.Sub-Department of EthologyUniversity of BirminghamBirminghamEngland
  2. 2.Central Toxicology LaboratoryImperial Chemical Industries Ltd.CheshireEngland

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