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Isoelectric Focusing of Human Saliva, Cerebrospinal Fluid, and Urine

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Biological and Biomedical Applications of Isoelectric Focusing

Part of the book series: Biological Separations ((BIOSEP))

Abstract

Isoelectric focusing has become an increasingly valuable technique in the study of proteins of extracellular body fluids, both at an analytical and a preparative level. Studies on salivary proteins involving the technique are now extensive, and they include investigations into the properties of purified salivary proteins as well as characterization of the protein patterns occurring in saliva as secreted. In the case of cerebrospinal fluid, the technique has been used almost exclusively as a means of investigating abnormalities in protein composition and the association of these with various neurological disorders. Studies on urine are at present somewhat limited, and here also investigators have been concerned with the correlation of abnormalities with pathological disorders.

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Authors and Affiliations

  1. Departments of Oral Biology and Biochemistry, University of Glasgow, Glasgow, G2 3JZ, Scotland, U.K.

    Josie A. Beeley

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  1. Massachusetts Institute of Technology, Cambridge, Massachusetts

    Nicholas Catsimpoolas

  2. Tufts University School of Medicine, Boston, Massachusetts

    James Drysdale

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Beeley, J.A. (1977). Isoelectric Focusing of Human Saliva, Cerebrospinal Fluid, and Urine. In: Catsimpoolas, N., Drysdale, J. (eds) Biological and Biomedical Applications of Isoelectric Focusing. Biological Separations. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4181-9_1

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