Abstract
The oligosaccharide prosthetic groups of glycoproteins are highly complex polymers consisting of several different monosaccharides arranged in both linear and branched arrays. The linkage between two sugars in these arrays can be either α or β and can occur between the anomeric carbon of one sugar and three to four possible carbons of the other sugar. In short, as has been frequently pointed out, the number of theoretical structures for even the shortest oligosaccharides is astronomical. As more information on glycoprotein structure becomes available (Montreuil, 1975), it is beginning to appear that although cells are capable of assembling an impressive number of different oligosaccharide structures, there are certain controlling features in the process which put definite limits on the types of structures that are made.
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Schachter, H. (1977). Control of Biochemical Parameters in Glycoprotein Production. In: Elstein, M., Parke, D.V. (eds) Mucus in Health and Disease. Advances in Experimental Medicine and Biology, vol 89. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4172-7_8
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