Abstract
The derangements in production and secretion of gastric mucus consist of:
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1)
Quantitative changes in concentration and output of mucus;
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2)
Qualitative changes in its composition;
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3)
Increased shedding of the mucus-containing surface epithelial cells and excessive extrusion of the mucus from the cells;
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4)
Abnormalities in the biosynthesis of glycoproteins of the mucus.
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References
Abelev, G.I., Perova, S.D., Kramkova, N.J., Postnikova, Z.A. and Irlin, I.S. (1963). Transplantation, 1, 174.
Aird, I. and Benthall, H.H. (1953). Brit.Med.J., 1, 799.
Aird, I., Benthall, H.H., Mehigan, J.A. and Roberts, J.A.F. (1954). Brit.Med. J., 2, 315.
Aird, I. and 19 associates (1956). Brit.Med.J., 2, 723.
André, F., Descos, F., André, C. and Lambert, R. (1976).Biol. Gastroent., Paris, (in press).
Avery-Jones, Sir Francis and Sullivan, F.M. (Eds.) (1972). Carbenoxolone in Gastroenterology, Butterworth & Co., London, pp.1–88.
Azzopardi, J.G. and Evans, D.C. (1966). J.Clin.Path., 19, 368.
Banjo, C., Gold, P., Freedman, S.O. and Krupey, J. (1972). Nature New Biol., 238, 183.
Banjo, C., Gold, P., Gehrke, C.W., Freedman, S.O. and Krupey, J. (1974). Int. J.Cancer, 13, 151.
Baraona, E., Pirola, R.C. and Lieber, C.S. (1974) Gastroenterol., 66, 226.
Beck, J.T. (Ed.) (1976). North American Symposium on Carbenoxolone: Excerpta Medica, 1975, Montreal, Canada, pp.1–186.
Bobak, L., Zwierz, K., Badurski, J., Ito, H. and Glass, G.B.J. (1974). Gastroenterol., A-13, 667, (Abstr.).
Bollet, A.J. (1961). Arthritis Rheum., 4, 624.
Burtin, P. (1974). Cancer, 34, 829.
Carlborg, I., Dahlgren, S. and Nordgren, B. (1970). Scand.J. Gastroenterol., 5, 427.
Chernick, W.S. and Barbero, G.J. (1963). Ann.N.Y.Acad.Sci., 106, 698.
Chey, W.Y. (1972). Digestion, 7, 239
Clarke, C.A., Covan, W.K., Howe11-Evans, A.W., McConnel, R.B., Woodrow, J.C. and Sheppard, P.M. (1955). Brit.Med.J., 1, 603.
Cooke, A.R. (1976). Am. J. Digest. Dis., 21, 155.
Croft, N.D. (1963). Brit.Med.J., 2, 897
Culling, C.F.A., Reid, P.E., Burton, J.D. and Dunn, W.L. (1975). J.Clin.Path., 28, 656.
Curt, J.R.N, and Pringle, R. (1969). Gut, 10, 931.
Davenport, H.W. (1967). Proc.Soc.Exp.Biol.Med., 126, 657
Davenport, H.W. (1968). Gastroenterol., 54, 175.
Davenport, H.W. (1970). in, Progress in Gastroenterology, (Ed.) G.B.J. Glass, vol.2, 42–56, Grune & Stratton, New York, N.Y.
Davenport, H.W. (1972). Digestion, 5, 162.
Dekanski, J.B., MacDonald, A., Sacra, P. and Parke, D.V. (1975). Brit.J.Pharmac., 55, 387.
Dinoso, V.P., Chey, W.Y., Siplet, H. and Lorber, S.H. (1970). Am.J.Dig.Dis., 15, 809.
Dinoso, V.P., Ming, S.C. and McNiff, J. (1976). Am.J.Dig.Dis., 21, 626.
Di Sant’Agnese, P.A.,. Dische, Z. and Danilchenco, A. (1957). Pediatrics, 19, 252.
Doll, R., Drane, H. and Newell, A.C. (1961). Gut, 2, 352.
Domschke, W., Domschke, S., Classen, M. and Demling, L. (1972). Scand.J.Gastroenterol., 7, 647.
Eastwood, G.L. and Kirchner, J.P. (1974). Gastroenterol., 67, 71.
Edginton, T.S., Astarita, R.W. and Plow, E.F. (1975). N.Eng.J. Med., 293, 103.
Filipe, M.I. (1969). Gut, 10, 577.
Filipe, M.I. (1971). Gut, 12, 418, (Abstr.).
Filipe, M.I. and Dawson, J. (1970). Gut, 11, 229.
Fischer, R.P., Jelense, S. and Fulton, R.L. (1976). Surgery, 80, 40.
Forstner, G. and Galand, G. (1976). Can.J.Biochem., 54, 224.
Fräser, G.M. and Clamp, J.R. (1975). Gut, 16, 832.
Gerard, A. (1965). C.R.Soc.Biol. (France), 159, 1473.
Gietka, J. (1964). Pol.Arch.Med.Wewnentrz., 34, 555.
Gitlin, D., Perricelli, A. and Gitlin, G. (1972). Cancer Res., 32, 979.
Glass, G.B.J. (1976). Mucus and gastric injury, in North American Symposium on Carbenoxolone, (Ed.) Beck, J.T., pp.29–43, Excerpta Medica, Amsterdam and Princeton.
Glass, G.B.J., Barowsky, H. and Schwartz, S.A. (1951). Gastroenterol., 19, 829.
Glass, G.B.J, and Boyd, L.J. (1950). Gastroenterol., 16, 697.
Glass, G.B.J, and Ishimori, A. (1961). Amer.J.Digest.Dis., 6, 103.
Glass, G.B.J., Ishimori, A. and Buckwalter, J.A. (1962). Gastroenterol., 42, 443.
Glass, G.B.J., Mori, H. and Pamer, I. (1969). Digestion, 2, 134.
Glass, G.B.J., Nieburgs, H.E., Hitzelberger, A.L. and Telatar, H. (1960). Clin.Res., 8, 200. (Abstr.).
Glass, G.B.J, and Pitchumoni, C.S. (1975). Human Pathol, 6, 219.
Glass, G.B.J, and Stremple, J.F. (1973). Lancet, 1, 1506.
Glowacka, D., Kopacz-Jodczyk, T., Mazurkiewicz-Kilczewska, D. and Gindzienski, A. (1974). Biochem.Med., 11, 199
Gold, J.M., Banjo, C., Freedman, S.O. and Gold, P. (1973). J. Immunol., 111, 1872.
Gold, P. and Freedman, S.O. (1965a). J.Exp.Med., 121, 439.
Gold, P. and Freedman, S.O. (1965b). J.Exp.Med., 122, 467.
Gold, P.H., Krupey, J. and Ansari, H. (1970). J.Nat.Cancer Inst., 45, 219.
Goodman, M.J., Kent, P.W. and Truelove, S.C. (1975). Gut, 16, 833
Greco, V., Lauro, G., Fabbrini, A. and Torsoli, A. (1967). Gut, 8, 491.
Grossman, M.I., Matumoto, K.K. and Lichter, H.J. (1961). Gastroenterol., 40, 383.
Häkkinen, J.P.T. (1967). Scand.J.Gastroenterol., 2, 39.
Häkkinen, J.P.T. (1972). Immunochem., 9, 1115.
Häkkinen, J.P.T., Jarvi, O. and Gronroos, J. (1968a). Int.J. Cancer, 3, 572.
Häkkinen, J.P.T., Johansson, R. and Pantio, M. (1968b). Gut, 9, 712.
Häkkinen, J.P.T., Korhonen, L.K. and Saxen, L. (1968c). Int.J. Cancer, 3, 582.
Häkkinen, J.P.T. and Virtanen, S. (1967). Clin.Exp.Immunol., 2, 669.
Hayashi, T., Ito, H. and Glass, G.B.J. (1974). Proc.5th World Congr.Gastroenterol., Mexico City.
Hellstrom, H.R. and Fisher, E.R. (1967). Am.J.Clin.Path., 48, 259.
Hirszfeld, L., Halber, U. and Hosenblatt, J. (1932). Z.Immunitäts- forsch., 75, 209.
Hitzelberger, A.L. and Glass, G.B.J. (1962). J.Lab.Clin.Med., 59, 575.
Holburn, A.M., Mach, J.P., MacDonald, D. and Newlands, M. (1974). Immunol., 26, 831.
Hollander, F. (1954) Arch.Int.Med., 93, 107
Horowitz, M.I. and Hollander, F. (1961). J.Biol.Chem., 236, 770.
Hoskins, L.C. and Zamcheck, N. (1965). Gastroenterol., 48, 758.
Huitric, E. (1973). Ann.Immunol. (Inst.Pasteur), 124C, 603.
Ivey, K.J., Den Besten, L. and Clifton, J.A. (1970). Gastroenterol. 59, 683.
Janowitz, H.D., Weinstein, V.A., Shaer, R.G. and Cereghini, J.F. (1958). Gastroenterol., 34, 11.
Johansson, H. and Lindquist, B. (1971). Scand.J.Gastroenterol., 6, 49
Johnson, L.R. (1966). Proc.Soc.Exp.Biol.Med., 121, 384.
Kawasaki, H., Nakayamo, K. and Kimoto, E. (1975). Gann., 66, 427
Kawashima, K. and Glass, G.B.J. (1973). Gastroenterol., 64, 752 (Abstr.).
Kawashima, K. and Glass, G.B.J. (1975). Am.J.Dig.Dis., 20, 162.
Kent, P.W. and Allen, A. (1968). Biochem.J., 106, 645
Kim, Y.S. and Isaacs, R. (1975). Cancer Res., 35, 2092.
Kim, Y.S., Isaacs, R. and Perdomo, J. (1974). Proc.Nat.Acad.Sci. (U.S.), 71, 4869.
Kim, Y.S., Kerr, R. and Lipkin, M. (1967) Nature, 215, 1180.
Kleist von, S. and Burtin, P. (1966). C.R. Acad.Sc. Paris, 263, 1543.
Kleist von, S. and Burtin, P. (1969). Cancer Res., 29, 1961.
Kleist von, S., Chavanel, G. and Burtin, P. (1972).Proc.Nat. Acad.Sci. (U.S.A.), 69, 2492.
Kleist von, S., King, M. and Burtin, P. (1974). Immunochem., 11, 249.
Kowalewski, K., Chmura, G., Dent, C. and Schier, J. (1969). Am.J. Dig.Dis., 14, 788.
Kowalewski, K. and Schier, J.F. (1971). Acta Gastroenterol.Belg., 34, 361.
Kowalewski, K. and Strutz, W.A. (1959). Acta Endocr. (Kobenhaven), 31, 107.
Kozlowska, K. (1970). Ztschr.Mikroskop.-anat.Forsch., 82, 219.
Krasner, N., Thomson, T.J., Crean, G. and McNeil, C. (1974).Gut, 15, 336 (Abstr.).
Krupey, J., Gold, P.H. and Freedman, S.O. (1967). Nature, (London), 215, 67.
Kurtz, S.M., Davis, T.D. and Ruffin, J.M. (1962). Lab.Invest., 11, 653.
Lambert, R. and André, C. (1972). Digestion, 5, 116.
Lambert, R., André, C. and Berard, A. (1971). Digestion, 4, 234.
Lambert, R., André, C., Leonard, J.P. and Martin, F. (1967). Acta Gastroenterol.Belg., 30, 787.
Lambert, R., André, C. and Martin, F. (1969). Gastroenterol., 68, 285.
Lambert, R., Martin, F., André, C., Descos, L. and Vouillon, G. (1968). Am.J.Digest.Dis., 13, 941.
LaMont, J.T., Weiser, M.M. and Isselbacher, K.J. (1974). Cancer Res., 34, 3225.
Lehy, T., Dufougeray, F. and Neuburger, P. (1972). Am.J.Digest. Dis., 17, 767.
Lev, R. (1970). in, Progress in Gastroenterology, (Ed.) Glass, G.B.J., Vol.11, pp.13–4l, Grune and Stratton, New York and London.
Lev, R., Kawashima, K. and Glass, G..B.J. (1976). Arch.Pathol. Lab.Med., 100, 554.
Lev, R., Siegel, H.I. and Glass, G.B.J. (1969). Cancer, 23, 1086.
Lev, R., Siegel, H.I. and Glass, G.B.J. (1970). Gastroenterol., 58, 495.
Lev, R., Siegel, H.I. and Glass, G.B.J. (1972). Gastroenterol., 62, 970.
Lev, R. and Spicer, S.S. (1965). Am.J.Path., 46, 23.
Lucas, C., Sugawa, C., Friend, W., Riddle, J. and Walt, A. (1972). Am.J.Surg., 123, 25.
Ludwig, W. and Lipkin, M. (1969). Gastroenterol., 56, 895.
Marcus, D.M. (1969). N.Eng.J.Med., 280, 994.
Martin, F. and Martin, M.S. (1970). Int.J.Cancer, 6, 352.
Max, M. and Menguy, R. (1969). Digestion, 2, 67.
Max, M. and Menguy, R. (1970). Gastroenterol., 58, 329.
McClelland, R., Shires, G. and Prager, M. (1971). Am.J.Surg., 121, 134
Menguy, R. and Desbaillets, L. (1967). Proc.Soc.Exp.Biol.Med., 125, 1108.
Menguy, R. and Desbaillets, L. (1968). Ann.Surg., 168, 475
Menguy, R. and Masters, Y.F. (1963). Surgery, 54, 19
Mersereau, W.A. and Hinchey, E.J. (1973). Gastroenterol., 64, 1130.
Mian, N., Cowen, D.M. and Nutman, C.A. (1974). Br.J.Cancer, 30, 231.
Mori, H., Stremple, J.F. and Glass, G.B.J. (1976).Biol.Gastroent (in press).
Osborne, R.H. and DeGeorge, F.V. (1962). Am.J.Hum.Genet., 14, 199
Pacheva, G., Kadian, H. and Bakalow, V. (1965). Europ.Congr. Gastroenterol., Budapest, (Abstr.), 280.
Pamer, T. (1968). Ph.D. Thesis, Graduate School of Medical Science, New York Medical College.
Pamer, T., Glass, G.B.J, and Horowitz, M.I. (1968). Biochem., 7, 3821.
Perry, K.H. (1968). Arch.Int.Pharmacodyn.Ther., 176, 337
Pitchumoni, C.S. and Glass, G.B.J. (1976). Biol.Gastroenterol. (Paris), 9, 11.
Pitchumoni, C.S. and Glass, G.B.J. (1977). in, Progress in Gastroenterology, (Ed.) G.B.J. Glass, Vol.III, (in- Press), Grune & Stratton, New York.
Pitchumoni, C.S., Lopes, J.D. and Glass, G.B.J. (1975). Am.J. Gastroent., 64, 187
Pringle, R. and Curt, J.R.N. (1971). Gut, 12, 418 (Abstr.).
Reid, P.E., Culling, C.F.A., Dunn, W.L., Ramey, C.W. and Clay, M.G. (1975). Can.J.Biochem., 53, 1328.
Roberts, S., Hefferman, C. and Douglas, A.P. (1975). Clin.Chim. Acta, 63, 121.
Rubin, E., Rybak, B., Lindenbaum, J., Gerson, C.D., Walker, G. and Lieber, C.S. (1972). Gastroenterol., 63, 801.
Sanders, L.D., Chandler, A.M. and Johnson, L.R. (1975). Gastroenterol., 68, 285.
Schrager, J. and Oates, M.D.G. (1973). Gut, 14, 324
Schrager, J. and Oates, M.D.G. (1974). Biochim.Biophys.Acta, 372, 183.
Stremple, J.F., Mori, H., Lev, R. and Glass, G.B.J. (1973). in, Current Problems in Surgery, (Ed.) Ravitch, M., Chicago, pp. 1–64.
Subbuswamy, S.G. (1971). Gut, 12, 200.
Takagi, K. and Yano, S. (1972). Chem.Pharm.Bull., 20, 1170.
Tatarinov, Y.S. (1964). Biochem.Congr., USSR, 2, 274 (Abstr.).
Uriel, J. and de Nechand, B. (1972). Ann.Inst.Pasteur, 122, 829.
Waldron-Edwards, D., Robert, L., Robert, A.M. and Bader, J.P. (1975). Biol.Gastroenterol., (Paris), 8, 117 (Abstr.).
Webster, D.R. (1967). in, Gastric Secretion. Mechanisms and Control, (Ed.) Shnitka, T.K., pp.215–235, Oxford, Pergamon Press.
Willems, G., Gerard, A. and Verbeustel, S. (1970). Biol. Gastroenterol., (Paris), 2, 125.
Witebsky, E. (1929). Z.Immunitätsforsch., 62, 59
Yano, S., Patkowska, M. and Glass, G.B.J. (1976). In Press.
Zwierz, K., Badurski, J., Gindzienski, A. and Kaczmarski, M. (1967). Gastroenterologia, 108, 197
Zwierz, K., Gindzienski, A., Badurski, J. and Popowicz, J. (1968). Digestion, 1, 183.
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Glass, G.B.J., Slomiany, B.L. (1977). Derangements of Biosynthesis, Production and Secretion of Mucus in Gastrointestinal Injury and Disease. In: Elstein, M., Parke, D.V. (eds) Mucus in Health and Disease. Advances in Experimental Medicine and Biology, vol 89. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4172-7_23
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