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Genetic Polymorphism of Chicken 7S Immunoglobulins

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Avian Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 88))

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Abstract

We have previously described five 7S immunoglobulin (Ig) heavy (H) chain allotypic specificities which are inherited among highly inbred chicken lines as codominant genetic traits segregating at an autosomal locus (1–4). These allotypes have been divided into two groups by structural analysis: a) Specificities CS-1.1 and CS-1.2 are present in the Fd portion of the 7S Ig H chain probably in a region analogous to the CJQ domain of mammaliany chains; and b) specificities CS-1.3, CH-1.4, and CS-1.5 are located in a region of the IS Ig H chain which is sensitive to papain digestion (2, 3).

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© 1977 Plenum Press, New York

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Wakeland, E.K., Foppoli, J.M., Benedict, A.A. (1977). Genetic Polymorphism of Chicken 7S Immunoglobulins. In: Benedict, A.A. (eds) Avian Immunology. Advances in Experimental Medicine and Biology, vol 88. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4169-7_34

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  • DOI: https://doi.org/10.1007/978-1-4613-4169-7_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4171-0

  • Online ISBN: 978-1-4613-4169-7

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