Postreplication Repair in Human Fibroblasts
Postreplication repair is defective in fibroblasts from all the xeroderma pigmentosum (XP) complementation groups with the exception of group E, the defect being most pronounced in the excision-proficient XP variants. It is normal in cells from patients with a variety of other disorders. During postreplication repair pyrimidine dimer sites become associated with daughter strands in both normal and XP cells.
KeywordsExcision Repair Pyrimidine Dimer Basal Cell Nevus Syndrome Daughter Strand Postreplication Repair
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