Postreplication Repair in Human Fibroblasts

  • A. R. Lehmann
  • S. Kirk-Bell
  • C. F. Arlett


Postreplication repair is defective in fibroblasts from all the xeroderma pigmentosum (XP) complementation groups with the exception of group E, the defect being most pronounced in the excision-proficient XP variants. It is normal in cells from patients with a variety of other disorders. During postreplication repair pyrimidine dimer sites become associated with daughter strands in both normal and XP cells.


Excision Repair Pyrimidine Dimer Basal Cell Nevus Syndrome Daughter Strand Postreplication Repair 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • A. R. Lehmann
    • 1
  • S. Kirk-Bell
    • 1
  • C. F. Arlett
    • 1
  1. 1.MRC Cell Mutation UnitUniversity of SussexFalmer, BrightonEngland

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