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Immunocytochemistry of Neuropeptides and Their Receptors

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Peptides in Neurobiology

Part of the book series: Current Topics in Neurobiology ((CTNB))

Abstract

Peripheral cells talk to each other via hormones. The message, although diffused into the bloodstream, is picked up selectively by those groups of cells that possess specific receptors for it. Neurons also talk to each other via hormones. By virtue of the axonal networks, they are able to direct a message to receptors on specific synapses with heightened selectivity and specificity. Thus, anatomical structure in the nervous system has added a relay system to the hormonal communication system found in the periphery. Immunocytochemistry provides simple and rapid means to differentiate axons as to the neurotransmitters carried, thereby permitting distinction among dopaminergic, serotonergic, and noradrenergic fibers.

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  1. Immunology Branch, Edgewood Arsenal, Maryland, USA

    Ludwig A. Sternberger

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  1. Ludwig A. Sternberger
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  1. Section on Functional Neurochemistry, Behavioral Biology Branch, National Institute of Child Health and Human Development, National Institutes of Health, 20014, Bethesda, Maryland, USA

    Harold Gainer

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© 1977 Plenum Press, New York

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Sternberger, L.A. (1977). Immunocytochemistry of Neuropeptides and Their Receptors. In: Gainer, H. (eds) Peptides in Neurobiology. Current Topics in Neurobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4130-7_4

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  • DOI: https://doi.org/10.1007/978-1-4613-4130-7_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4132-1

  • Online ISBN: 978-1-4613-4130-7

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