Immunocytochemistry of Neuropeptides and Their Receptors

  • Ludwig A. Sternberger
Part of the Current Topics in Neurobiology book series (CTNB)


Peripheral cells talk to each other via hormones. The message, although diffused into the bloodstream, is picked up selectively by those groups of cells that possess specific receptors for it. Neurons also talk to each other via hormones. By virtue of the axonal networks, they are able to direct a message to receptors on specific synapses with heightened selectivity and specificity. Thus, anatomical structure in the nervous system has added a relay system to the hormonal communication system found in the periphery. Immunocytochemistry provides simple and rapid means to differentiate axons as to the neurotransmitters carried, thereby permitting distinction among dopaminergic, serotonergic, and noradrenergic fibers.


Luteinizing Hormone Tyrosine Hydroxylase Paraventricular Nucleus Median Eminence Arcuate Nucleus 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Ludwig A. Sternberger
    • 1
  1. 1.Immunology BranchEdgewood ArsenalUSA

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