Monoamine Oxidase, Monoamine-Oxidase-Inhibiting Drugs, and Human Behavior

  • Dennis L. Murphy


Monoamine-oxidase- (MAO)-inhibiting drugs, which reduce the oxidative deamination of the brain biogenic amine neurotransmitters, were the first effective antidepressant agents used in medicine. Although there have been many studies of the clinical efficacy of these agents, there have been only a handful of reports examining their other effects on human behavior and psychological function. There are also only a small number of studies of the effects of in vivo treatment with MAO-inhibiting drugs on human monoamine oxidase activity.


Monoamine Oxidase Schizophrenic Patient Monoamine Oxidase Activity Chronic Schizophrenic Patient Amine Oxidase Activity 
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© Plenum Press, New York 1987

Authors and Affiliations

  • Dennis L. Murphy
    • 1
  1. 1.Clinical Neuropharmacology BranchNational Institute of Mental HealthBethesdaUSA

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