Abstract
At a major conference on the amygdala held in 1972 (Elefethriou 1972) the total number of putative transmitters known to be present in the amygdala was three. These were noradrenaline, serotonin and acetylcholine (Eidelberg and Woodbury 1972). Only in the case of the cholinergic system, where acetylcholinesterase staining had been carried out (Shute and Lewis, 1967) was there any data on regional distribution within the amygdala. Since this date a number of studies, primarily in the rat, have examined the distribution of neurotransmitters within the amygdala. In this brief review an attempt has been made to summarize recent data from our laboratory on the amino acid distribution in the rat amygdala and also to present data on the distribution of putative peptide neurotransmitters within the amygdala.
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References
Azmitia, E., 1978, The serotonin producing neurons of the median and dorsal raphe, in “Handbook of Psychopharmacology (L.L. Iversen, S.D. Iversen and S.H. Snyder, eds.) (in press).
Ben-Ari,Y., Le Gal La Salle, G., Emson, P., Barbin, G., and Garbarg, M., 1977, Neurochemical mapping of transmitter candidate systems in the amygdaloid complex and bed nucleus of the stria terminalis of the rat, Proc. International Physiological Sciences, Vol. XIII, Abst. 177.
Brownstein, M., Palkovitz, M., Saavedra, J., Bassiri, R., and Utiger, R., 1974, Thyrotropin releasing hormone in specific nuclei of the brain. Science 185: 267–269.
Brownstein, M.J., Palkovitz, M., Saavedra, J.M., and Kizer, J.S., 1975, Tryptophan hydroxylase in the rat brain, Brain Research 97: 163–166.
Conrad, L., Leonard, C., and Pfaff, D., 1974, Connections of the median and dorsal raphe nuclei in the rat. An autoradiographic and degeneration study. J. comp Neurol. 156: 179–206.
Egger, M.D., 1972, Amygdaloid-hypothalamic neurophysiological interrelationships, in “The Neurobiology of the Amygdala”, (B.E. Eleftheriou, ed.), Plenum Press, New York.
Eidelberg, E., and Woodbury, C.M., 1972, Electrical activity in the amygdala and its modification by drugs. Possible nature of synaptic transmission, a review in “Neurobiology of the Amygdala”, (B.E. Eleftheriou, ed.), Plenum Press, New York.
Eleftheriou, B.E., 1972, Neurobiology of the amygdala, Plenum Press, New York.
Emson, P.C., Paxinos, G., Jessell, T.M., and Cuello, A.C., 1978, Substance P in the amygdaloid complex, bed nucleus and stria terminalis system of the rat brain, Brain Research (submitted for publication).
Emson, P.C., Paxinos, G., and Bjørklund, A., 1978, Effects of ventral amygdofugal pathway and stria terminalis lesions on the distribution of 5-hydroxytryptamine, dopamine and noradrenaline in the amygdaloid nuclei. A histochemical and biochemical study, (in preparation).
Epelbaum, J., Brazeau, J., Tsang, D., Brawer, J., and Martin, J.B., 1977, Subcellular distribution of radioimmunoassayable somatostatin in rat brain, Brain Research 126: 309–323.
Fuxe, K., Hökfelt, T., Said, S.I., and Mutt, V., 1977, Vasoactive intestinal polypeptide and the nervous system: immunohisto- chemical evidence for localization in central and peripheral neurons particularly intracortinal neurons of the cerebral cortex, Neuroscience Letters, (in press).
Hökfelt, T., Johansson, O., Kellerth, J.O., Ljungdahl, A., Nilsson, G., Nyards, A., and Pernow, B., 1977, Immunohistochemical distribution of substance P, in “Substance P” (U.S. von Euler and B. Pernow, eds.), Raven Press, New York.
Kanazawa, I., and Jessell, T., 1976, Post mortem changes and regional distribution of substance P in the rat and mouse nervous system, Brain Research 117: 362–367.
Lindvall, O., and Björklund, A., 1974, The organization of the ascending catecholamine neuron systems in the rat brain, Acta Physiol. Scand. Supp. 412.
McGeer, P.L., McGeer, E.G., Scherer, U., and Singh, K., 1977, A glutamatergic corticostriatal pathway, Brain Research 128: 369–373.
Nilson, G., Hökfelt, T., and Pernow, B., 1974, Distribution of substance P-like immunoreactivity in the rat central nervous system as revealed by immunohistochemistry, Med. Biol., 52: 424–427.
Otsuka, M., and Takahashi, T., 1977, Putative peptide neurotransmitters, in “Annual Review of Pharmacology”, Vol. pp 425–439.
Shute, C.C.D., and Lewis, P.R., 1967, The ascending cholinergic reticular system: neocortical olfactory and subcortical projections, Brain 90: 497–520.
Snyder, S.H., Uhl, G.R., and Kuhar, M.J., 1977, Comparative features of enkephalin and neurotensin in the mammalian central nervous system, in Centrally Acting Peptides” (J. Hughes, ed.) Macmillan, (in press).
Storm-Mathisen, J., 1976, Localization of putative neurotransmitters in the hippocampal formation, Experimental Brain Research Suppl. 1: 179–187.
Swanson, L.W., 1977, Immunohistochemical evidence for a neurophysin-containing autonomic pathway arising in the paraventricular nucleus of the hypothalamus, Brain Research 128: 346–353.
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Emson, P.C. (1978). Neurotransmitters in the Amygdala: A Brief Review. In: Fonnum, F. (eds) Amino Acids as Chemical Transmitters. NATO Advanced Study Institutes Series, vol 16. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4030-0_14
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DOI: https://doi.org/10.1007/978-1-4613-4030-0_14
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