Abstract
Adult polycystic kidney disease (APKD) is a genetic disease inherited in autosomal dominant fashion. The penetrance of the gene is such that most patients carrying it will have pathologic evidence of the disease by age eighty (1). There is no sex predilection and the etiology is unknown. The disease typically manifests itself in middle age but may appear as early as infancy. Pathologically, APKD is characterized by bilateral renal cysts. Approximately one-third of the patients with APKD also will have cysts of the liver (2) and cysts in other organs occur less commonly (3). Since patients with APKD may not manifest the disease until their 4th decade or later, the detection of pre-symptomatic APKD is of potential importance in genetic counseling.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Dalgaard, O.Z., Bilaterial Polycystic Disease of the Kidneys. A follow up of two hundred eighty four and their families. ACTA Med. Scand. Suppl. 328, 1957.
Dalgaard, O.Z. Polycystic Disease of the Kidneys, in Strauss, M.B. and Welt, L.G. (Eds.). Boston: Little, Brown, 1971, pp. 12–23.
Banovitch, G.M., Clinical Features and Pathophysiology. Polycystic Disease in Man, in Gardner, K.D. (ed.), Cystic Diseases of the Kidney. New York: John Wiley and Sons, Inc., 1976, pp. 125–150.
Taylor, K.J.W., Hill, C.R., Scanning Techniques in Grey-Scale Ultrasonography. Br. J. Radiol. 48:918–920, 1975.
Rosenfield, A.T., Curtis, McB.A., Putman, C.E., Taylor, K.J.W., Allen, W.E. III, Siegel, J.N., Hsia, E.Y., Grey-Scale Ultrasonography, Computerized Tomography, and Nephrotomography in Evaluation of Polycystic Kidney and Liver Disease. Urology 9:436–438, 1977.
Lufkin, E.G., Alfred, A.C., Trucksess, M.D., and Holmes, J.H., Polycystic Kidney Disease — Earlier Diagnosis Using Ultrasound. Urology 4:5–12, 1974.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 American Institute of Ultrasound in Medicine and Plenum Press, New York
About this chapter
Cite this chapter
Rosenfield, A.T., Taylor, K.J.W., Wolf, B., Gottlieb, S., Rosenfield, N.S., Hsia, Y.E. (1978). Ultrasound in the Pre-Symptomatic Diagnosis of Adult (Dominant) Polycystic Kidney Disease. In: White, D., Lyons, E.A. (eds) Ultrasound in Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4021-8_37
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4021-8_37
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4023-2
Online ISBN: 978-1-4613-4021-8
eBook Packages: Springer Book Archive