Abstract
The causes of periodic breathing with its alternating phases of crescendo and decrescendo breathing remains controversial. One recent paper suggests that the periodicity might be caused by the activity of a central nervous system oscillator that affects both respiratory and circulatory systemsl. Another view is that periodic breathing results from instability in the negative feedback system which adjusts ventilation to keep PC0 2, P0 2 and 2p3 in the blood and brain interstitial fluid within narrow limitsl, 2, 3 Accordingly, periodic breathing would be analogous to instabilities that occur in predictable circumstances in physical automatic control systems producing a constantly cycling output5. The same kinds of conditions which cause instability in physical systems would be expected to produce periodic breathing in the respiratory system.
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© 1978 Plenum Press, New York
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Cherniack, N.S., von Euler, C., Homma, I., Kao, F.F. (1978). Effects Of Increased Respiratory Controller Gain During Hypoxia And Hypercapnia on Periodic Breathing In Cats. In: Fitzgerald, R.S., Gautier, H., Lahiri, S. (eds) The Regulation of Respiration During Sleep and Anesthesia. Advances in Experimental Medicine and Biology, vol 99. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4009-6_45
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DOI: https://doi.org/10.1007/978-1-4613-4009-6_45
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