Central Mechanisms Controlling Expiratory Duration

  • Morton I. Cohen
  • Jack L. Feldman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 99)


One of the major problems in the study of respiratory rhythm is the nature of the mechanisms which produce the abrupt transitions (phase-switching) between the expiratory (E) and inspiratory (I) phases, and which are closely related to the mechanisms determining the durations of the respective phases. In recent years, the attention of researchers has been focussed mainly on the mechanisms of I --> E switching and the control of I phase duration (TI), especially with regard to the role of pulmonary afferents (PA) in the Breuer-Hering I-inhibitory reflex1–8. The analogous problem of the nature of the mechanisms controlling E --> I switching and E phase duration (TE) has been studied to a lesser extent; in the present paper we present some data and hypotheses relevant to this problem.


Afferent Input Phase Duration Stimulus Train Lung Inflation Nucleus Ambiguus 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Morton I. Cohen
    • 1
  • Jack L. Feldman
    • 1
  1. 1.Department of PhysiologyAlbert Einstein College of Medicine Bronx, New YorkPhiladelphiaUSA

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