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Blood Levels of Cadaverine and its Metabolites Monoacetylcadaverine and Monopropionylcadaverine in Psychotic Subgroups of Schizophrenics

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Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Abstract

Cadaverine (1,5-diaminopentane) has been the least studied biogenic diamine in mammals. The presence of other polyamines in animal tissues in much higher concentrations than cadaverine was one reason for this preferential attention (1). In addition to the reported absence of cadaverine in the brain (2) it has been assumed that if detected, the presence of cadaverine was the result of either microbial metabolism in the intestine (3) or of tissue putrefaction (4).

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References

  1. U. Bachrach, “Function of the Naturally Occurring Polyamines”, Academic Press, New York, 1973.

    Google Scholar 

  2. S.I. Harik, G.W. and S.H. Snyder, in “Polyamines in Normal and Neoplastic Growth”, Raven Press, New York, 1973.

    Google Scholar 

  3. H. Tabor and C.W. Tabor, Adv. Enzymol. Mol. Biol., 1972, 36, 203.

    Google Scholar 

  4. F. Dreyfuss, R. Chayen, G. Dreyfuss, R. Dvir and J. Ratan, Israel J. Med. Sci., 1975, 11, 785.

    Google Scholar 

  5. H. Dolezalova, M. Stepita-Klauco and R. Fairweather, Brain Res., 1974, 77, 166.

    Article  Google Scholar 

  6. H. Dolezalova and M. Stepita-Klauco, in “Advances in Mass spectrometry in Biochemistry and Medicine”, Vol. 1, A. Frigerio and N. Castagnoli, Eds., Spectrum, New York, 1976, p. 207.

    Google Scholar 

  7. S. Henningsson, L. Persson and E. Rosengren, Acta Physiol. Scand., 1976, 98, 445.

    Article  Google Scholar 

  8. F. Picolli and A. Lajtha, Biochim. Biophys. Acta, 1971, 225, 356.

    Google Scholar 

  9. M. Stepita-Klauco and H. Dolezalova, Nature, London, 1974, 252, 158.

    Article  Google Scholar 

  10. T.H. Perry, S. Hansen and L. MacDougall, Nature, London, 1967, 214, 484.

    Article  Google Scholar 

  11. H. Dolezalova, M. Stepita-Klauco, J. Kucera, H. Uchimura and M. Hirano, in “Mass Spectrometry in Drug Metabolism, A. Frigerio and L. Ghisalberti, Eds., Plenum, New York, 1977, p. 201.

    Google Scholar 

  12. American Psychiatric Association, “DSM-II Diagnostic and Statistical Manual of Mental Disorders”, 2nd ed., Washington, D.C., 1968.

    Google Scholar 

  13. N. Seiler, Methods Biochem. Anal., 1970, 18, 259.

    Google Scholar 

  14. J.R. Majer and A.A. Boulton, Nature, London, 1970, 225, 658.

    Article  Google Scholar 

  15. A.A. Boulton and J.R. Majer, J. Chromatogr., 1970, 48, 322.

    Article  Google Scholar 

  16. N.M. Frew and T.L. Isenhour, Anal. Chem., 1972, 44, 659.

    Article  Google Scholar 

  17. A.A. Boulton, S.R. Philips and D.A. Durden, J. Chromatogr., 1973, 82, 137.

    Article  Google Scholar 

  18. N. Seiler and B. Knodgen, Org. Mass Spectrom., 1973, 7, 97.

    Article  Google Scholar 

  19. A. Nies, D.S. Robinson, J.M. Davis and C.L. Ravaris, Psychosom. Med., 1971, 33, 470.

    Google Scholar 

  20. D.L. Murphy and R. Weiss, Am. J. Psychiatry, 1972, 128, 1351.

    Google Scholar 

  21. D.L. Murphy and R.J. Wyatt, Nature, London, 1972, 238, 225.

    Article  Google Scholar 

  22. R.J. Wyatt, D.L. Murphy, R. Belmaker, S. Cohen, C.H. Donnelly and V. Pollin, Science, 1973, 179, 916.

    Article  Google Scholar 

  23. H.Y. Meitzer and S.M. Stahl, Res. Commun. Chem. Pathol. Pharmacol., 1974, 7, 419.

    Google Scholar 

  24. A. Nies, D.S. Robinson, L.S. Harris and K.R. Lamborn, Adv. Biochem. Psycho-pharmacol., 1974, 12, 59.

    Google Scholar 

  25. I.B. Cookson, F. Own and A.P. Ridges, Psychol. Med., 1975, 5, 314.

    Article  Google Scholar 

  26. E.A. Zeller, B. Boshes, J.M. Davis and M. Thorner, Lancet, 1975, 1, 1385.

    Article  Google Scholar 

  27. J.J. Schildkraut, J.M. Herzog, P.J. Orsulak, S.E. Edelman, H.M. Shein and S.H. Frazier, Am. J. Psychiatry, 1976, 133, 438.

    Google Scholar 

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© 1978 Plenum Press, New York

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Dolezalova, H., Stepita-Klauco, M., van der Velde, C.D., Cassone, V.M. (1978). Blood Levels of Cadaverine and its Metabolites Monoacetylcadaverine and Monopropionylcadaverine in Psychotic Subgroups of Schizophrenics. In: Frigerio, A. (eds) Recent Developments in Mass Spectrometry in Biochemistry and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3991-5_24

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  • DOI: https://doi.org/10.1007/978-1-4613-3991-5_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3993-9

  • Online ISBN: 978-1-4613-3991-5

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