Abstract
Epstein-Barr virus (EBV), a member of the herpes group of viruses, is the cause of heterophil-posi- tive infectious mononucleosis, of some heterophil-negative cases, and of occasional cases of tonsillitis and pharyngitis in childhood. Rarely, it may produce involvement of the central nervous system. This virus is strongly implicated as having a causal relationship to African Burkitt lymphoma and to nasopharyngeal cancer. High antibody titers are also present in 40–50% of cases of Hodgkin’s disease, sarcoidosis; and systemic lupus erythematosus.
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References
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Suggested Reading
Carter, R. L., and Penman, H. G. (eds.). Infectious Mononucleosis, Blackwell, Oxford, 1969.
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Hoagland, R., Infectious Mononucleosis, Grune and Stratton, New York, 1967.
Klein, G., The Epstein-Barr Virus in Herpesviruses (A. S. Kaplan, ed.). Academic Press, New York, 1973.
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Evans, A.S., Niederman, J.C. (1976). Epstein-Barr Virus. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3988-5_9
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