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Smallpox

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Viral Infections of Humans

Abstract

Smallpox is a serious systemic disease which may kill 40–50% of the unprotected individuals it afflicts. The disease has a characteristic exanthem and disfigures and sometimes blinds most of the survivors. A closely related poxvirus, that of variola minor (or alastrim), causes a similar exanthem but less severe illness and the case fatality rate is 2% or less.

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Suggested Reading

  • Benenson, A. S., Routine vaccination for all is still indicated, in: Controversy in Internal Medicine II (F. J. Ingelfinger, R. V. Ebert, M. Finland, and A. J. Relman, eds.), pp. 371–381, Saunders, Philadelphia, 1974.

    Google Scholar 

  • Christie, A. B., Infectious Diseases: Epidemiology and Clinical Practice, pp. 185–237, E. and S. Livingston, Edinburgh, 1969.

    Google Scholar 

  • Dick, G., Smallpox: A reconsideration of public health policies. Prog. Med. Virol. 8: 1–29 (1966).

    PubMed  CAS  Google Scholar 

  • Dixon, C. W., Smallpox, J. and A. Churchill, London, 1962.

    Google Scholar 

  • Downie, A. W., Smallpox, in: Infectious Agents and Host Reactions (S. Mudd, ed.), pp. 487–518, Saunders, Philadelphia, 1970.

    Google Scholar 

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Authors and Affiliations

  1. Department of Community Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA

    Abram S. Benenson

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  1. Abram S. Benenson
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  1. Yale University, USA

    Alfred S. Evans

  2. WHO Serum Reference Bank, Section of International Epidemiology, New Haven, Connecticut, USA

    Alfred S. Evans

  3. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA

    Alfred S. Evans

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Benenson, A.S. (1976). Smallpox. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3988-5_20

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