Abstract
The parainfluenza viruses are species of the paramyxovirus family. (3,43) They are exceeded only by respiratory syncytial virus as important causes of lower respiratory disease in young children, and they commonly reinfect older children and adults to produce upper respiratory illnesses. There is considerable diversity in both epidemiological and clinical manifestations of infections due to the parainfluenza viruses. Parainfluenza virus type 1 (Para 1) is the principal cause of croup (laryngotracheobronchitis) in children, and parainfluenza virus type 3 (Para 3) is second only to RS virus as a cause of pneumonia and bronchiolitis in infants less than 6 months of age. Parainfluenza virus type 2 (Para 2) resembles type 1 in clinical manifestations, but serious illnesses occur less frequently; infections with parainfluenza virus type 4 (Para 4) are detected infrequently and associated illnesses are usually inconsequential.
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Suggested Reading
Chanock, R. M., and Parrott, R. H., Acute respiratory disease in infancy and childhood: Present understanding and prospects for prevention. Pediatrics 36: 21–39 (1965).
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Jackson, G., and Muldoon, R., Viruses causing com-mon respiratory infections in man. II. Enteroviruses and paramyxoviruses, J. Infect. Dis. 128: 387–469 (1973).
Monto, A.. The Tecumseh study of respiratory illness. V. Patterns of infection with the parainfluenza viruses. Am. J. Epidemiol. 97: 338–348 (1973).
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Glezen, W.P., Loda, F.A., Denny, F.W. (1976). The Parainfluenza Viruses. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3988-5_15
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