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Hypersensitive Serotonergic Receptors Involved in Clinical Depression—A Theory

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Neuropharmacology and Behavior

Abstract

As many investigators will attest, developing and conducting a research program in the field of mental health is a very difficult task. It is only in the last 20 years that a few hints have appeared in the literature from animal research in the fields of neuropharmacology and neurochemical correlates of behavior that give the researcher any leads on which to base an active clinical-basic research program. These ideas have led to some important clinical studies that will be referred to below. It is interesting that some recent work with animal models of depression has again provided the research clinician with new insights for further experimentation.

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Authors and Affiliations

  1. Section of Applied and Theoretical Neurobiology, Institute of Psychiatric Research, Indiana University Medical Center, 46202, Indianapolis, Indiana, USA

    M. H. Aprison & K. Tachiki

  2. Department of Neuropsychiatry, Nagasaki University School of Medicine, Nagasaki, Japan

    Ryo Takahashi

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  1. M. H. Aprison
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  2. Ryo Takahashi
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  3. K. Tachiki
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Editors and Affiliations

  1. The Marine Biomedical Institute Department of Human Biological Chemistry and Genetics and Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA

    Bernard Haber

  2. Institute of Psychiatric Research and Departments of Psychiatry and Biochemistry, Indiana University School of Medicine, Indianapolis, Indiana, USA

    M. H. Aprison

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Aprison, M.H., Takahashi, R., Tachiki, K. (1978). Hypersensitive Serotonergic Receptors Involved in Clinical Depression—A Theory. In: Haber, B., Aprison, M.H. (eds) Neuropharmacology and Behavior. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3961-8_2

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  • DOI: https://doi.org/10.1007/978-1-4613-3961-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3963-2

  • Online ISBN: 978-1-4613-3961-8

  • eBook Packages: Springer Book Archive

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