Skip to main content

Poxviruses

  • Chapter
Molecular Virology
  • 225 Accesses

Abstract

Poxviruses are the largest viruses among the members of Taxa A and B. The virions that replicate in the host cell cytoplasm contain a double-stranded DNA genome of 130–240 × 106 daltons and more than 30 proteins, including an enzyme, a DNA-dependent RNA polymerase. The virion proteins elicit antibodies to at least 10 antigens. One antigen is common to all the members of this virus family.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Bibliography

  • Becker, Y., and Joklik, W.K. Messenger RNA in vaccinia infected cells. Proc. Natl. Acad. Sci. USA 51: 577–585, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Becker, Y., and Sarov, I. Electron microscopy of vaccinia virus DNA. J. Mol. Biol. 34: 655–660, 1968.

    Article  PubMed  CAS  Google Scholar 

  • Cooper, J.A.; Moss, B.; and Katz, E. Inhibition of vaccinia virus late protein synthesis by isatin-f3-thiosemicarbazone: characterization and in-vitro translation of viral mRNA. Virology 96: 381–392,1979.

    Article  PubMed  CAS  Google Scholar 

  • Dumbell, K.R., and Archard, L.C. Comparison of white pock (h) mutants of monkeypox virus with parental monkeypox and with variola-like viruses isolated from animals. Nattlre 286: 29–32, 1980.

    Article  CAS  Google Scholar 

  • Esposito, J.J.; Obijeski, J.F.; and Nakano, J.H. Orthopoxvirus DNA: strain differentiation by electrophoresis of restriction endonuclease fragmented virion DNA. Virology 89: 53–66, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Ghendon, Y.Z., and Chernos, V.I. Mutants of poxviruses resistant to acetone and N-methylisatin-beta-thiosemicarbazone. Acta Virol. 16: 308–312, 1972.

    PubMed  CAS  Google Scholar 

  • Joklik, W.K. The multiplication of poxvirus DNA. Cold Spring Harbor Symp. Quant. Biol. 27: 199–208, 1962.

    CAS  Google Scholar 

  • Kates, J., and McAuslan, B.R. Poxvirus DNA-dependent RNA polymerase. Proc.Natl. Acad. Sci. USA 58: 134–141,1967.

    Article  PubMed  CAS  Google Scholar 

  • Machett, M., and Archard, L.C. Conservation and variation in orthopoxvirus genome structure. J. Gen. Virol. 45: 683–701, 1979.

    Article  Google Scholar 

  • McAuslan, B. R. The induction and repression of thymidine kinase in the poxvirus infected HeLa cell. Virology 21: 383–389, 1963.

    Article  PubMed  CAS  Google Scholar 

  • Urushibara, T.; Nishimura, C.; and Miura, K.-I. Process of cap formation of messenger RNA by vaccinia virus particles carrying an organized enzyme system. J. Gen. Virol. 52: 49–59, 1981.

    Article  PubMed  CAS  Google Scholar 

  • Wittek, R.; Barbosa, E.; Cooper, J.A.; Garon, CF.; Chan, H.; and Moss, B. Inverted terminal repetition in vaccinia virus DNA encodes early mRNAs. Nature 285: 21–25, 1980.

    Article  PubMed  CAS  Google Scholar 

Recommended Reading

  • Bauer, D.J. Thiosemicarbazone. International Encyclopedia of Pharmacology and Therapeutics. Section 61. Chemotherapy of Virus Diseases. Vol. 1. New York, Pergamon Press, 1972, pp. 35–113.

    Google Scholar 

  • Baxby, D. The origins of vaccinia virus. J. Infect. Dis. 136: 453–455, 1977.

    Article  PubMed  CAS  Google Scholar 

  • Cho, CT., and Wenner, H.A. Monkeypox virus. Bact. Rev. 37: 1–18, 1973.

    PubMed  CAS  Google Scholar 

  • Downie, A.W. Poxvirus group. In: Viral and Rickettsial Infections of Man. (F.L. Horsfall and I. Tamm, eds.), pp. 932–964. J.B. Lippincott Co., 1965.

    Google Scholar 

  • Fenner, F. The eradication of smallpox. Prog. Med. Virol. 23: 1–21, 1977.

    PubMed  CAS  Google Scholar 

  • Follett, E.A.C, and Pennington, T.H. The mode of action of rifamycins and related compounds on poxvirus. Adv. Virus Res. 18: 105–142, 1973.

    Article  CAS  Google Scholar 

  • Moss, B. Reproduction of poxviruses. In: Comprehmsive Virology (H. Fraenkel-Conrat and R.R. Wagner, eds.), Plenum Press, New York, 1974, Vol. 3, pp. 405–474.

    Google Scholar 

  • Wilcox, W.C, and Cohen, G.H. The poxvirus antigens. Curr. Top. Microbiol. Immunol. 47: 1–19, 1969.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Julia Hadar

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Martinus Nijhoff Publishers, The Hague

About this chapter

Cite this chapter

Becker, Y., Hadar, J. (1983). Poxviruses. In: Hadar, J. (eds) Molecular Virology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3906-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-3906-9_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3908-3

  • Online ISBN: 978-1-4613-3906-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics