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Experience with Adrenal Cortical Carcinoma in Children

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Part of the book series: Cancer Treatment and Research ((CTAR,volume 17))

Abstract

Cancers of the adrenal cortex most commonly present with virilization or as Cushing’s syndrome, depending on whether they secrete androgens or Cortisol [1, 2]. Very rarely, tumors of the adrenal cortex in children may cause feminization or aldosterone secretion [3, 4]. Tumor size is quite variable at the time of diagnosis, since many are detected when they are quite small because of the excessive hormone secretion [5]. Although metastasis is rare, it can occur in association with malignant lesions.

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References

  1. Cahill GF, Melecow MM, Darby HH: Adrenal Cortical Tumors: The Types of Non-Hormonal and Hormonal Tumors. Surg Gynecol Obstet 74: 281–305, 1942.

    Google Scholar 

  2. Fraumine JF, Miller RW: Adrenal Cortical Neoplasias and Hemihypertrophy, Brain Tumors and Other Disorders. J Pediatr 70: 129–138, 1967.

    Article  Google Scholar 

  3. Higgins GH, Brounlee WE, Monty FH: Feminizing Tumors on the Adrenal Cortex. Am Surg 22: 56–79, 1956.

    PubMed  CAS  Google Scholar 

  4. Cavell B, Sandegard E, Hakfelt B: Primary Aldosteronism Due to an Adrenal Adenoma in the Three Year Old Child. Acta Paediatr Scand 53: 205–212, 1964.

    Article  CAS  Google Scholar 

  5. Clayton GW: Tumors of the Endocrine Glands. In: Clinical Pediatric Oncology, Mosby CV, 1977 (2nd edition), p 525–540.

    Google Scholar 

  6. Johnson GJ, Summerskill, Anderson VE, Keating FR: Clinical and Genetic Investigation of a Large Kindred with Multiple Endocrine Adenomatosis. N Engl J Med 277: 1379–1385, 1967.

    Article  PubMed  CAS  Google Scholar 

  7. Steiner AL, Goodman AD, Powers SR: Study of a Kindred with Pheochromocytoma, Medullary Thyroid Carcinoma, Hyperparathyroidism and Cushing Disease, Multiple Endocrine Neoplasia, Type 2. Med 47: 371–409, 1968.

    Article  CAS  Google Scholar 

  8. Block MA: A Component of an Interesting Endocrine Syndrome. CA-A Cancer Journal for Clinicians 19: 74–79, 1969.

    Article  PubMed  CAS  Google Scholar 

  9. Khaire MRA, Dexter RN, Burgynski NJ, Johnston CC: Mucosal Neuroma, Pheochromocytoma, and Medullary Thyroid Carcinoma. Med 54: 89–112, 1975.

    Google Scholar 

  10. Carney JA, Go VLW, Sizemore GW, Hayles AB: Alimentary Tract Ganglioneuromatosis: A Major Component of the syndrome of Multiple Endocrine Neoplasia, Type 2B. N Engl J Med 295: 1287–1291, 1976.

    Article  PubMed  CAS  Google Scholar 

  11. Grosfield JL, Clatworthy HW, Hamoudi AB: Pancreatic Malignancy in Childhood. Arch Surg 101: 370–375, 1970.

    Google Scholar 

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© 1983 Martinus Nijhoff Publishers, Boston

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Morgan, E.R., Baum, E.S., West, P.M. (1983). Experience with Adrenal Cortical Carcinoma in Children. In: Humphrey, G.B., Grindey, G.B., Dehner, L.P., Acton, R.T., Pysher, T.J. (eds) Adrenal and Endocrine Tumors in Children. Cancer Treatment and Research, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3891-8_17

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  • DOI: https://doi.org/10.1007/978-1-4613-3891-8_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3893-2

  • Online ISBN: 978-1-4613-3891-8

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