Abstract
Adrenocortical carcinoma (ACC) is an uncommon neoplasm in the pediatric age group, occurring in fewer than 15 children per year in the United States [1]. Many of these tumors are hormonally active, producing a variety of presenting manifestations [2, 3]. Features at diagnosis include an abdominal mass, facial acne, growth acceleration, deepening of the voice, growth of axillary and pubic hair, precocious genital development, and hypertension. Because of the rarity of the tumor in children, accurate survival statistics are difficult to ascertain. In a series of 49 adult patients, death due to metastatic disease occurred in 73% [4].
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© 1983 Martinus Nijhoff Publishers, Boston
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Hutchinson, R.J., Heyn, R.M. (1983). Adrenocortical Carcinoma in Children. In: Humphrey, G.B., Grindey, G.B., Dehner, L.P., Acton, R.T., Pysher, T.J. (eds) Adrenal and Endocrine Tumors in Children. Cancer Treatment and Research, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3891-8_15
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DOI: https://doi.org/10.1007/978-1-4613-3891-8_15
Publisher Name: Springer, Boston, MA
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