Role of Radiotherapy

  • Robert D. Lindberg
Part of the Cancer Treatment and Research book series (CTAR, volume 15)


The role of radiation therapy in the treatment of adult soft tissue sarcomas has undergone a transition during the past two decades. Until recently, radical surgical excision has been considered the only curative treatment since soft tissue sarcomas were known to be ‘radioresistant.’ This concept of radioresistance was based on early published reports. In 1928, Rostock [1] reported on a collected series of 505 patients with soft tissue sarcoma. Although 78% of the sarcomas responded favorable immediately following irradiation, only 2.9% of the patients were cured as compared to a 30%, 5-year cure rate in another group of 550 patients treated by surgery alone. Thus, the concept of ‘radioresistance’ was firmly established and surgery became the treatment of choice.


Soft Tissue Sarcoma Conservation Surgery Extremity Soft Tissue Sarcoma Extremity Lesion Adult Soft Tissue Sarcoma 
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© Martinus Nijhoff Publishers, Boston/The Hague/Dordrecht/Lancaster 1983

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  • Robert D. Lindberg

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