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Ultrastructure of Rathke’s pituitary cleft

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Ultrastructure of Endocrine Cells and Tissues

Part of the book series: Electron Microscopy in Biology and Medicine ((EMBM,volume 1))

Abstract

Rathke’s pituitary cleft represents the original recess of so-called Rathke’s pouch derived in the embryo from the ectodermal evagination of the stomodeum (1,2). In several mammals, for example the rat, dog and cat, this recess persists during postnatal life as a wide fissure separating the pars distalis from the pars intermedia. It is lined by a continuous layer of cells termed ‘marginal cells’, and contains a fluid-like material (colloid) of uncertain function, origin and chemical composition (3).

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References

  1. Hamilton WJ, Boyd JD, Mossman HW: Human embryology, 4th edit., W Heffer & Sons Ltd, Cambridge, 1973.

    Google Scholar 

  2. Langman J: Medical Embryology. Human development, normal and abnormal. 3rd edit. The Williams & Wilkins Company, Baltimore, 1975.

    Google Scholar 

  3. Kurosumi K, Fujita H: Functional Morphology of endocrine glands. An atlas of electron micrographs. Igaku-Shoin Ltd, Tokyo, 1975, pp 1–377.

    Google Scholar 

  4. Dubois P, Girod C: Observation au microscope électronique d’un reliquat de la fente hypophysaire chez la hamster doré adulte. Cr Séanc Soc Biol (Paris) 164: 157–160, 1970.

    CAS  Google Scholar 

  5. Vanha-Perttula T, Arstila AV: On the epithelium of the rat pituitary residual lumen. Z Zellforsch 108: 487–500, 1970.

    Article  PubMed  CAS  Google Scholar 

  6. Dingemans KP, Feltkamp CA: Non granulated cells in the mouse adenohypophysis. Z Zellforsch 124: 387–405, 1972.

    Article  PubMed  CAS  Google Scholar 

  7. Ciocca DR, Gonzales CB: The pituitary cleft of the rat. An electron microscopic study. Tissue and Cell 10: 725–733, 1978.

    Article  PubMed  CAS  Google Scholar 

  8. Ciocca DR: Scanning electron microscopy of the cleft of the rat pituitary. Cell Tissue Res 206: 139–143, 1980.

    Article  PubMed  CAS  Google Scholar 

  9. Yoshimura F, Soji T, Kiguchi Y: Relationship between the follicular cells and marginal layer cells of the anterior pituitary. Endocrinol Jpn 24 (3): 301–305, 1977.

    Article  PubMed  CAS  Google Scholar 

  10. Kagayama M, Ando A, Yamamoto TY: On the epithelial lining of the cleft between pars distalis and pars intermedia in the mouse adenohypophysis. Gumna Symp Endocrinol 6: 125–136, 1969.

    Google Scholar 

  11. Sano M, Sasaki F: Embryonic development of the mouse anterior pituitary studied by light and electron microscopy. Z Anat Entw Gesch 129: 195–222, 1969.

    Article  CAS  Google Scholar 

  12. Vila-Porcile E: Le reasou des cellules folliculo-stellaires et les follicules de Tadenohypophyse du rat (pars distalis). Z Zellforsch 129: 328–369, 1972.

    Article  PubMed  CAS  Google Scholar 

  13. Correr S, Caggiati A, Motta P: Scanning electron microscopy of the rat hypophysary cleft. Proc 5th Europ Anat Congr September 10–14 (abstract) p 70, Prague, 1979.

    Google Scholar 

  14. Correr S, Motta PM: Relationship between the marginal layer and parenchymal cells of the rat adenohypophysis as revealed by scanning electron microscopy. Biomedical Research 2, supplement: 109–113, 1981.

    Google Scholar 

  15. Fujita H, Kataoka K: Electron microscopic observation on blood capillaries of the anterior pituitary of normal and acid dye-injected animals. Gumna Symp Endocrinol 6: 137–149, 1969.

    Google Scholar 

  16. Correr S, Caggiati S, Motta PM: Scanning and transmission electron microscopic observations of the rat hypophysary cleft. Folia Morphologica 28: 82–87, 1980.

    PubMed  CAS  Google Scholar 

  17. Andrews PM: A scanning electron microscopic study of the extrapulmonary respiratory tract. Am J Anat 139: 299–324, 1974.

    Article  Google Scholar 

  18. Smolich JJ, Stratford BF, Maloney JE, Ritchie BC: Postnatal development of the epithelium of larynx and trachea in the rat: scanning electron microscopy. J Anat 124: 657–673, 1977.

    PubMed  CAS  Google Scholar 

  19. Takor Takor T, Pearse AGE: Neuroectodermal origin of ovarian hypothalamo-hypophyseal complex. The role of the ventral neural ridge. J Embryol Exp Morphol 34: 311–325, 1975.

    Google Scholar 

  20. Pearse AGE: The cytochemistry and ultrastructure of polypeptide hormon-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. J Histochem Cytochem 17: 303–313, 1969.

    Article  PubMed  CAS  Google Scholar 

  21. Fujita T: Concept of paraneurons. Arch Histol Jp 40, Suppl 1–12, 1977.

    Google Scholar 

  22. Pearse AGE, Takor Takor T: Embryology of the diffuse neuroendocrine system and its relationship to the common peptides. Federation Proc 38: 2288–2294, 1979.

    CAS  Google Scholar 

  23. Cocchia D, Miani N: Immunocytochemical localization of the brain specific S-100 protein in the pituitary gland of adult rat. J Neurocytol 9: 771–782, 1980.

    Article  PubMed  CAS  Google Scholar 

  24. Kessel RG, Kardon RH: Tissues and organs. A text-atlas of scanning electron microscopy. WH Freeman and Co, San Francisco, 1979.

    Google Scholar 

  25. Allen DJ, Persky B, Low FN: Some regional variations in ventricular lining material in laboratory mammals and man. SEM: Vol II, Becker RP, Johari D (eds), SEM Inc AMF O’Hare, IL USA, 1978, pp 45–52.

    Google Scholar 

  26. Flament-Durand J, Vienne G, Dustin P: Scanning electron microscopic study of the ependyma of the hypothalamic region in man. SEM: Vol II, Becker RP, Johari D (eds), SEM Inc AMF O’Hare, IL USA, 1978, pp 151–156.

    Google Scholar 

  27. Mestres P: Old and new concepts about circumventricular organs: an overview. SEM: Vol II, Becker RP, Johari D (eds), SEM Inc AMF CTHare, IL USA, 1978, pp 137–142.

    Google Scholar 

  28. Hosoya Y, Fujita T: Scanning electron microscope observation of intra-ventricular macrophages (Kolmer cells) in the rat brain. Arch Histol Jpn 35: 133–140, 1973.

    PubMed  CAS  Google Scholar 

  29. Bleier R: Surface fine structure of supraependymal elements and ependyma of hypothalamic third ventricle of mouse. J Comp Neurol 161: 555–568, 1975.

    Article  PubMed  CAS  Google Scholar 

  30. Mestres P, Breipohl W: Morphology and distribution of supraependymal cells in the third ventricle of the albino rat. Cell Tissue Res 168: 303–314, 1976.

    Article  PubMed  CAS  Google Scholar 

  31. Coates PW: The third ventricle of monkeys: scanning electron microscopy of surface features in mature males and females. Cell Tissue Res 177: 307–316, 1977.

    Article  PubMed  CAS  Google Scholar 

  32. Allen DJ: Scanning electron microscopy of epiplexus macrophages (Kolmer cells) in the dog. J Comp Neurol 161: 197–214, 1975.

    Article  PubMed  CAS  Google Scholar 

  33. Dent JN, Gupta BL: Ultrastructural observations on the developmental cytology of the pituitary gland in the spotted newt. Gen Comp Endocrinol 8: 273–288, 1967.

    Article  PubMed  CAS  Google Scholar 

  34. Schechter J: The ultrastructure of the stellate cell in the rabbit pars distalis. Anat Rec 160: 422, 1968.

    Google Scholar 

  35. Cardell RR: The ultrastructure of stellate cells in the pars distalis of the salamander pituitary gland. Amer J Anat 126: 429–456, 1969.

    Article  PubMed  Google Scholar 

  36. Rinehart JF, Farquhar MG: The fine vascular organization of the anterior pituitary gland. An electron microscopic study with histochemical correlations. Anat Rec 121: 207–240, 1955.

    Article  PubMed  CAS  Google Scholar 

  37. Yamada K, Yamashita K: An electron microscopic study on the possible site of production of ACTH in the anterior pituitary of mice. Z Zellforsch 80: 29–43, 1967.

    Article  PubMed  CAS  Google Scholar 

  38. Van Blerkom J, Motta P: A scanning electron microscopic study of the luteo-follicular complex. III. Formation of the corpus luteum and repair of the ovulated follicle. Cell Tissue Res 189: 131–154, 1978.

    Article  PubMed  Google Scholar 

  39. Motta P, Muto M, Fujita T: Three-dimensional organization of mammalian adrenal cortex. A scanning electron microscopic study. Cell Tissue Res 196: 23–38, 1979.

    Article  PubMed  CAS  Google Scholar 

  40. Quay WB: Pineal canaliculi: demonstration, twenty-four-hour rhythmicity and experimental modification. Amer J Anat 139: 81–93, 1974.

    Article  PubMed  CAS  Google Scholar 

  41. Krstic R: Scanning electron microscope observations of the canaliculi in the rat pineal gland. Experientia (Basel) 31: 1072–1074, 1975.

    Article  CAS  Google Scholar 

  42. Motta PM, Calvieri S, Palermo D: On the occurrence of spaces similar to intercellular canaliculi in the Leydig cells of mice. Experientia (Basel) 29: 1120–1122, 1973.

    Article  CAS  Google Scholar 

  43. Motta P, Porter KR: Structure of rat liver sinusoids and associated tissue spaces as revealed by scanning electron microscopy. Cell Tissue Res 148: 111–125, 1974.

    Article  PubMed  CAS  Google Scholar 

  44. Motta P: The three-dimensional fine structure of the liver as revealed by scanning electron microscopy. Int Rev Cytol (Suppl 6). Studies in Ultrastructure. Academic Press, New York, San Francisco, London, 1977, pp 347–401.

    Google Scholar 

  45. Ottaviani G: Linfatico Sistema. In: Enciclopedia medica italiana, USE, Firenze, 1953, Vol 5, pp 1877–1881.

    Google Scholar 

  46. Harrison RG: The adrenal circulation. Blackwell, Oxford, 1960.

    Google Scholar 

  47. Brauer RW: Liver circulation and function. Physiol Rev 43: 115–213, 1963.

    PubMed  CAS  Google Scholar 

  48. Correr S, Motta PM: The pituitary cleft and associated parenchymal tissues in the rat adenohypophysis as revealed by scanning electron microscopy. In: Three-dimensional microanatomy of cells and tissue surfaces. Didio LJA, Motta PM, Allen DJ (eds), Elsevier North Holland, Inc, 1981, pp 167–181.

    Google Scholar 

  49. Farquhar MG: Processing of secretory products by cells of the anterior pituitary gland. In: Memoirs of the society for endocrinology. Heller H, Lederis K (eds), Cambridge University Press, N° 19 1971, pp 79–122.

    Google Scholar 

  50. Young BA, Foster CL, Cameron E: Some observations on the ultra- structure of the adenohypophysis of the rabbit. J Endocrinol 31: 279–287, 1965.

    Article  PubMed  CAS  Google Scholar 

  51. Barberini F, Sartori S, Van Blerkom J, Motta P: Changes in the surface morphology of the rabbit endometrium related to the estrous and progestational stages of the reproductive cycle. A scanning and trans-mission electron microscopic study. Cell Tissue Res 190: 207–222, 1978.

    Article  PubMed  CAS  Google Scholar 

  52. Enders AC, Nelson DM: Pinocytotic activity of the uterus of the rat. Am J Anat 138: 277–300, 1973.

    Article  PubMed  CAS  Google Scholar 

  53. Parr MB, Parr ELL: Endocytosis in the uterine epithelium of the mouse. J Reprod Fert 50: 151–153, 1977.

    Article  CAS  Google Scholar 

  54. Ketelbant-Balasse P, Rodesch F, Neve P, Pasteels JM: Scanning electron microscope observations of apical surfaces of dog thyroid cells. Exp Cell Res 79: 111–119, 1973.

    Article  CAS  Google Scholar 

  55. Nunez E, Wallis J, Gershon MD: Secretory processes in follicular cells of the bat thyroid. III. The occurrence of extracellular vesicles and colloid droplets during hibernation. Am J Anat 141: 179–202, 1974.

    Article  PubMed  CAS  Google Scholar 

  56. Motta P, Andrews PM, Porter KR: Microanatomy of cell and tissue surfaces. An atlas of scanning electron microscopy Lea & Febiger, Philadelphia, 1977.

    Google Scholar 

  57. Correr S, Motta PM: The rat pituitary cleft: a correlated study by scanning and transmission electron microscopy. Cell Tissue Res 215: 515–529, 1981.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Anatomy, Faculty of Medicine, University of Rome, Viale R. Elena 289, 00161, Rome, Italy

    Fabrizio Barberini & Silvia Correr

Authors
  1. Fabrizio Barberini
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  2. Silvia Correr
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Editors and Affiliations

  1. Department of Anatomy, Faculty of Medicine, University of Rome, Italy

    P. M. Motta M.D., Ph.D.

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© 1984 Martinus Nijhoff Publishers, Boston, The Hague, Dordrecht, Lancaster

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Barberini, F., Correr, S. (1984). Ultrastructure of Rathke’s pituitary cleft. In: Motta, P.M. (eds) Ultrastructure of Endocrine Cells and Tissues. Electron Microscopy in Biology and Medicine, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3861-1_5

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  • DOI: https://doi.org/10.1007/978-1-4613-3861-1_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3863-5

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