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The Pharmacology of a New Antiestrogen

  • James A. Clemens
  • Larry J. Black
  • Robert L. Zerbe
Part of the Developments in Oncology book series (DION, volume 23)

Abstract

Presently, attempts to pharmacologically antagonize estrogen action are impeded by the weak estrogenic activity of the currently available estrogen antagonists. Most antiestrogens, rather than being pure antagonists, possess varying degrees of estrogen agonist activity. Thus, the action of estrogens can be antagonized only to the point where the agonist activity of the antiestrogen begins to be expressed.

Keywords

Mammary Tumor Estradiol Benzoate Relative Binding Affinity Estradiol Benzoate Pure Antagonist 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Black LJ, Jones CD, Falcone JF: Antagonism of estrogen with a new benzothiophene antiestrogen. Life Sci (32): 1031–1036, 1983.PubMedCrossRefGoogle Scholar
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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • James A. Clemens
  • Larry J. Black
  • Robert L. Zerbe

There are no affiliations available

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