Abstract
Increasing knowledge of the mammalian cell surface and the advent of monoclonal antibodies have revived interest in treating cancer by the simple infusion of xenogeneic antibody. This approach can be monitored with precision, partly at the molecular level, in contrast to the popular immunotherapy of the 1970s in which attempts were made to invoke immune responses to autochthonous tumours. Furthermore the antibody infusion is relatively innocuous, with problems such as hypersensitivity fairly well understood. A large question remains, however, about its efficacy.
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© 1984 Martinus Nijhoff Publishing, Boston
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Stevenson, G.T., Cole, V.M., Glennie, M.J., Watts, H.F. (1984). Complement Lysis of Tumour Cells Induced by Univalent Antibodies. In: Harrap, K.R., Davis, W., Calvert, A.H. (eds) Cancer Chemotherapy and Selective Drug Development. Developments in Oncology, vol 23. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3837-6_37
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DOI: https://doi.org/10.1007/978-1-4613-3837-6_37
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