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Isomyosin Shifts in Normal and Induced Cardiac Growth

  • Ketty Schwartz
  • Jean-Jacques Mercadier

Abstract

Myosin is the most abundant protein of the contractile apparatus, representing approximately 60% of the total myofibrillar proteins. Each molecule of myosin is composed of two heavy chains (MHC, 200,000 daltons), two regulatory or phosphorylatable light chains (LC2,17,000 to 20,000 daltons), and two alkali light chains, non-phosphorylatable (LC1,29,000 to 22,000 daltons and, in skeletal muscles, LC3 15,000 to 16,000 daltons). The whole molecule can be cleaved in several regions or domains: sub-fragments 1 and 2 (S1 and S2), heavy meromyosin (HMM), and light meromyosin (LMM).

Keywords

Light Chain Heavy Chain Myosin Heavy Chain Cardiac Myosin Cardiac Growth 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Martinus Nijhoff Publishing, Boston/The Hague/Dordrecht/Lancaster 1984

Authors and Affiliations

  • Ketty Schwartz
  • Jean-Jacques Mercadier

There are no affiliations available

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