Hemostatic Abnormalities in Tumor-Bearing Animals

  • Maria Benedetta Donati
Part of the Developments in Oncology book series (DION, volume 22)


Although the first description of vascular thrombosis in cancer patients is more than one century old (1), several unresolved questions still remain on the involvement of the hemostatic system in malignancy. First, clinical studies have repeatedly demonstrated that malignant disease is associated with a high incidence of hemostatic disorders, ranging from isolated abnormalities of laboratory tests to vascular thrombosis, hemorrhage or overt disseminated intravascular coagulation (DIC). On the other hand, using different techniques, several investigators have shown the presence of fibrin deposits in and around tumors as a sign of the activation of clotting in malignancy (2–4).


Disseminate Intravascular Coagulation Disseminate Intravascular Coagulation Fibrinolytic Activity Microangiopathic Hemolytic Anemia Hemostatic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Martinus Nijhoff Publishing, Boston 1984

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  • Maria Benedetta Donati

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