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Experimental and Clinical Experience with Pyrimido-Pyrimidine Derivatives in the Inhibition of Malignant Metastasis Formation

  • Helmuth Gastpar
  • Julian L. Ambrus
  • Wilhelm van Eimeren
Chapter
Part of the Developments in Oncology book series (DION, volume 22)

Abstract

The fate of disseminated tumor cells in the circulation is largely determined by their physiochemical surface properties which are foreign to the blood and conditioned by the thromboplastic activities intrinsic to the tumor cell (1). The term “cancer cell stickiness” (2) describes a tumor-specific, population-variable property of the circulating tumor cells in terms of an increased tendency to adhere to foreign surfaces (3). Cell populations with a high degree of stickiness have a correspondingly high thromboplastic activity and transplantation rate (4,5).

Keywords

Adenylate Cyclase Circulate Tumor Cell Inhibit Platelet Aggregation Disseminate Tumor Cell Ehrlich Ascites Tumor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • Helmuth Gastpar
  • Julian L. Ambrus
  • Wilhelm van Eimeren

There are no affiliations available

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