Skip to main content
SpringerLink
Log in

Prostacyclin/Thromboxanes and Tumor Cell Metastasis

  • Chapter
Hemostatic Mechanisms and Metastasis

Part of the book series: Developments in Oncology ((DION,volume 22))

Abstract

The ability to metastasize is a characteristic which distinguishes benign from malignant neoplasms. Metastasis can be simply defined as a loss of contiguity between a tumor cell or a clump of tumor cells and the primary tumor with successful transfer to, and growth at, a spatially separate site. The overall process can be regarded as a series of sequential events representing complex interactions between the tumor cell and the host (Figure 1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hilgard P, Beyerle L, Hohage R, Hiemeyer V and Rubier M. Eur. J. Cancer 8: 347–352, 1972.

    Article  PubMed  CAS  Google Scholar 

  2. del Regato JA. Semin. Oncol. 4: 33–38, 1977.

    PubMed  Google Scholar 

  3. Fisher ER and Fisher B. Arch. Pathol. 83: 321–324, 1967.

    PubMed  CAS  Google Scholar 

  4. Fidler IJ, Gersten DM and Hart I. Adv. Cancer Res. 28: 149–250, 1978.

    Article  PubMed  CAS  Google Scholar 

  5. Weiss L. Semin. Oncol. 4: 5–17, 1977.

    PubMed  CAS  Google Scholar 

  6. Cole WH, Robert SS, Webb RS, Strehl FW and Oates GD. Ann. Surg. 161: 753–768, 1965.

    Article  PubMed  CAS  Google Scholar 

  7. Salsbury AJ. Cancer Treat. Rev. 2: 55–72, 1975.

    Article  PubMed  CAS  Google Scholar 

  8. Butler TP and Gullino PM. Cancer Res. 35: 512–516, 1975.

    PubMed  CAS  Google Scholar 

  9. Liotta LA, Kleinerman J and Saidel GM. Cancer Res. 34: 997–1004, 1974.

    PubMed  CAS  Google Scholar 

  10. Liotta LA, Kleinerman J and Saidel GM. Cancer Res. 36: 889–894, 1976.

    PubMed  CAS  Google Scholar 

  11. Lotan R and Raz A. Cancer Res. 43: 2088–2093, 1983.

    PubMed  CAS  Google Scholar 

  12. Glaves D. Br. J. Cancer 48: 665–673, 1983.

    Article  PubMed  CAS  Google Scholar 

  13. Weiss L. In: Tumor Invasion and Metastasis (Ed. Liotta LA and Hart IR), Martinus Nijhoff, The Hague, pp. 81–98, 1982.

    Google Scholar 

  14. Weiss L. Int. J. Cancer 25: 385–392, 1980.

    Article  PubMed  CAS  Google Scholar 

  15. Weiss L, Ward PM and Holmes JC. Int. J. Cancer 32: 79–83, 1983.

    Article  PubMed  CAS  Google Scholar 

  16. Sato H and Suzuki M. In: Fundamental Aspects of Metastasis (Ed. Weiss L), American Elsevier:New York, pp. 311–317, 1976.

    Google Scholar 

  17. Hanna N. Cancer Metastasis Rev. 1: 45–64, 1982.

    Article  PubMed  CAS  Google Scholar 

  18. Fidler IJ, Barnes Z, Fogler WE, Kirsh R, Bugelski P and Poste G. Cancer Res. 42: 496–501, 1982.

    PubMed  CAS  Google Scholar 

  19. Glaves D. Invasion Metastsis 3: 160–173, 1983.

    CAS  Google Scholar 

  20. Irimura T, Gonzalez R and Nicolson GL. Cancer Res. 41: 3411–3418, 1981.

    PubMed  CAS  Google Scholar 

  21. Irimura T and Nicolson GL. J. Supramol. Struct. Cell. Biochem. 17: 325–336, 1981.

    Article  PubMed  CAS  Google Scholar 

  22. Takacz JS and Lampen JO. Biochem. Biophys. Res. Commun. 65: 248–257, 1975.

    Article  Google Scholar 

  23. Takatsuki A, Kohno K and Tamura G. Agr. Biol. Chem. 39: 2089–2091, 1975.

    Article  CAS  Google Scholar 

  24. Murray JC, Liotta L, Rennard SI and Martin GR. Cancer Res. 40: 347–351, 1980.

    PubMed  CAS  Google Scholar 

  25. Terranova VP, Liotta LA, Russo RG and Martin GR. Cancer Res. 42: 2265–2269, 1982.

    PubMed  CAS  Google Scholar 

  26. Vlodavsky I and Gospodarowicz D. Nature (London) 289: 304–306, 1981.

    Article  CAS  Google Scholar 

  27. Shirrmacher V, Altervogt P, Fogel M, Dennis J, Walker CA, Barz D, Schwartz R, Cheingsong-Popov R, Springer G, Robinson PJ, Nebe T, Brossmer W, Vlodavsky I, Paweletz N, Zirrmermann HP and Uhlenbrach G. Invasion Metastasis 2: 313–360, 1982.

    Google Scholar 

  28. Zacharski LR, Rickles FR, Henderson WG, Martin JF, Forman WB, van Eeckhout JP, Cornell CJ and Forcier RJ. Am. J. Clin. Oncol. 5: 593–609, 1982.

    Article  PubMed  CAS  Google Scholar 

  29. Rickles FR and Edwards RL. Blood 62: 14–31, 1983.

    PubMed  CAS  Google Scholar 

  30. Laghi F, DiRoberto PF, Panici PB, Margariti PA, Scribano D, Cudillo L, Villani L and Bizzi B. Tumori 69: 349–353, 1983.

    PubMed  CAS  Google Scholar 

  31. Brain MC, Azzopardi JG, Baker LRI, Pinco GF, Roberts PD and Dacic JV. Br. J. Haematol. 18: 183–190, 1970.

    Article  PubMed  CAS  Google Scholar 

  32. Donati MB and Poggi A. Br. J. Haematol. 44: 173–182, 1980.

    Article  CAS  Google Scholar 

  33. Harker LA and Slichter SJ. N. Eng. J. Med. 287: 999–1005, 1972.

    Article  CAS  Google Scholar 

  34. Gasic GJ, Boettiger D, Catalfamo JL, Gasic TB and Stewart GJ. Cancer Res. 38: 2950–2955, 1978.

    PubMed  CAS  Google Scholar 

  35. Karpatkin S, Smerling A and Pearlstein E. J. Lab. Clin. Med. 96: 994–1001, 1980.

    PubMed  CAS  Google Scholar 

  36. Pearlstein E, Cooper LB and Karpatkin S. J. Lab. Clin. Med. 93: 332–344, 1979.

    PubMed  CAS  Google Scholar 

  37. Pearlstein E, Salk PL, Yogeeswaran G and Karpatkin S. Proc. Natl. Acad. Sci. USA 77: 4336–4339, 1980.

    Article  PubMed  CAS  Google Scholar 

  38. Curatolo L, Colucci M, Canibini AL, Poggi A, Morasca L, Donati MB and Sejeraro N. Br. J. Cancer 40: 228–233, 1979.

    Article  PubMed  CAS  Google Scholar 

  39. Gordon SG and Cross BA. J. Clin. Invest. 67: 1665–1671, 1981.

    Article  PubMed  CAS  Google Scholar 

  40. Gordon SG, Franks JJ and Lewis B. Thromb. Res. 6: 127–137, 1975.

    Article  PubMed  CAS  Google Scholar 

  41. Cavanaugh PG, Sloane BF, Bajkowski AS, Gasic TB, Gasic GJ and Honn KV. Clin. Exp. Metastasis 4: 297–307, 1983.

    Article  Google Scholar 

  42. Fidler IJ. Eur. J. Cancer 9: 223–227, 1973.

    Article  PubMed  CAS  Google Scholar 

  43. Liotta LA, Kleinerman J and Saidel GM. Cancer Res. 36: 889–894, 1976.

    PubMed  CAS  Google Scholar 

  44. Gorelik E, Berc WW and Herberman RB. Int. J. Cancer 33: 87–94, 1984.

    Article  PubMed  CAS  Google Scholar 

  45. Gastpar H. J. Med. 8: 103–114, 1977

    PubMed  CAS  Google Scholar 

  46. Gasic GJ, Gasic TB and Stewart CC. Proc. Natl. Acad. Sci. USA 61: 46–52, 1968.

    Article  PubMed  CAS  Google Scholar 

  47. Sindelar WR, Tralka TS and Ketcham AS. J. Surg. Res. 18: 137–161, 1975.

    Article  PubMed  CAS  Google Scholar 

  48. Gasic GJ, Gasic TB, Galanti N, Johnson T and Murphy S. Int. J. Cancer 11: 704–718, 1973.

    Article  PubMed  CAS  Google Scholar 

  49. Honn KV, Cicone B and Skoff A. Science 212: 1270–1272, 1981.

    Article  PubMed  CAS  Google Scholar 

  50. HonnKV. Clin. Exp. Metastasis 1: 103–114, 1983.

    Article  PubMed  CAS  Google Scholar 

  51. Honn KV, Busse WD and Sloane BF. Biochem. Pharmacol. 32: 1–11, 1983.

    Article  PubMed  CAS  Google Scholar 

  52. Honn KV, Meyer J, Neagos G, Henderson T, Westley C and Ratanatharathorn V. In: Interaction of Platelets and Tumor Cells (Ed. Jamieson GA), Alan R. Liss: New York, pp. 295–331, 1982.

    Google Scholar 

  53. Lione A and Bosmann HB. Cell Biol. Int. Rep. 82: 81–86, 1978.

    Article  Google Scholar 

  54. Maat B and Hilgard P. J. Cancer Res. Clin. Oncol. 101: 275–283, 1981.

    Article  PubMed  CAS  Google Scholar 

  55. Colucci M, Delnini F, DeBelles Vitti G, Locati D, Poggi A, Semeraro N and Donati MB. Biochem. Pharmacol. 32: 1689–1691, 1983.

    Article  PubMed  CAS  Google Scholar 

  56. Maniglia CA, Tudor G, Gomez J and Sartorelli AL. Cancer Lett. 16: 253–260, 1982.

    Article  PubMed  CAS  Google Scholar 

  57. Gasic GJ, Viner ED, Budzynski AZ and Gasic GP. Cancer Res. 43: 1633–1636, 1983.

    PubMed  CAS  Google Scholar 

  58. Zacharski LR, Henderson WG, Rickles FR, Forman WB, Cornell Jr. CJ, Forcier RJ, Harrower HW and Johnson RO. Cancer 44: 732–741, 1979.

    Article  PubMed  CAS  Google Scholar 

  59. Vargaftig BB, Chignard M and Benveniste J. Biochem. Pharmacol. 30: 263 - 271, 1981.

    Article  PubMed  CAS  Google Scholar 

  60. Hamberg M, Svensson J and Samuelsson B. Proc. Natl. Acad. Sci. USA 72: 2994–2998, 1975.

    Article  PubMed  CAS  Google Scholar 

  61. Gorman RR. Fed. Proc. Fed. Am. Soc. Exp. Biol. 38: 83–88, 1979.

    CAS  Google Scholar 

  62. Heptinstall S, Bevan J, Cockbill SR, Hanley SP and Parry MJ. Thromb. Res. 29: 219–230, 1980.

    Article  Google Scholar 

  63. Rybicki JP and LeBreton GC. Thromb. Res. 30: 407–414, 1983.

    Article  PubMed  CAS  Google Scholar 

  64. Mbncada S, Gryglewski RJ, Bunting S and Vane JR. Nature (London) 263: 663–665, 1976.

    Article  Google Scholar 

  65. Moncada S and Vane JR. In: Advances in Prostaglandin and Thromboxane Research (Eds. Samuelsson B, Ransvell PW and Paoletti R), Raven Press:New York, Vol. 6, pp. 43–60, 1980.

    Google Scholar 

  66. Moncada S and Vane JR. In: Biochemical Aspects of Prostaglandins and Thromboxanes (Eds. Kharasch N and Fried J), Academic Press:New York, pp. 155–177, 1977.

    Google Scholar 

  67. Millane KM, Dusting GJ, Salmon JA, Moncada S and Vane JR. Eur. J. Pharmacol. 54: 217–228, 1979.

    Article  Google Scholar 

  68. Moncada S, Gryglewski RJ, Bunting S and Vane JR. Prostaglandins 12: 715–733, 1976.

    Article  PubMed  CAS  Google Scholar 

  69. Szczeklik A and Gryglewski RJ. In: Clinical Pharmacology of Prostacyclin (Eds. Lewis PJ and O’Grady J), Raven Press:New York, pp. 159–167, 1981.

    Google Scholar 

  70. Menter DG, Onoda JM, Taylor JD and Honn KV. Cancer Res. 44: 450–456, 1984.

    PubMed  CAS  Google Scholar 

  71. Lerner WA, Pearlstein E, Anbrogio C and Karpatkin S. Int. J. Cancer 31: 463–469, 1983.

    CAS  Google Scholar 

  72. Bastida E, Ordinas A, Giardina SL and Jamieson GA. Cancer Res. 42: 4348–4352, 1982.

    PubMed  CAS  Google Scholar 

  73. Pearlstein E, Ambrogio C, Gasic G and Karpatkin S. Cancer Res. 41: 4535–4539, 1981.

    PubMed  CAS  Google Scholar 

  74. Bennett A, Berstock DA, Raja B and Stamford IF. Br. J. Riarmacol. 66: 415P, 1979.

    Google Scholar 

  75. Bennett A, DelTacca M, Stamford IF and Zebro T. Br. J. Cancer 35: 881–884, 1977.

    Article  PubMed  CAS  Google Scholar 

  76. Feller N, Malachi T and Halbrecht I. J. Cancer Res. Clin. Oncol. 93: 275–280, 1979.

    Article  PubMed  CAS  Google Scholar 

  77. Rolland PH, Martin PM, Jacquemier J, Rolland AM and Toga M. J. Natl. Cancer Inst. 64: 1061–1070, 1980.

    PubMed  CAS  Google Scholar 

  78. Humes JL and Strausser HR. Prostaglandins 5: 183–197, 1974.

    Article  CAS  Google Scholar 

  79. Dowsett M, Easty GS, Powles TJ, Easty DM and Neville AM. Prostaglandins 11: 447–460, 1976.

    Article  PubMed  CAS  Google Scholar 

  80. Tashjian AH, Voekel EF and Levine L. Prostaglandins 14: 309–317, 1977.

    Article  PubMed  CAS  Google Scholar 

  81. Plescia DJ, Smith AN and Grinwich K. Proc. Natl. Acad. Sci. USA 72: 1848–1851, 1975.

    Article  PubMed  CAS  Google Scholar 

  82. Powles TJ, Coonibes RC, Munro-Neville A, Ford H and Gazet JC. Lancet 2: 138, 1977.

    Article  PubMed  CAS  Google Scholar 

  83. Maclntyre DE. In: Platelets in Biology and Pathology (Ed. Gordon JL), Elsevier/North Holland:Amsterdam, Vol. 2, pp. 211–247, 1981.

    Google Scholar 

  84. Honn KV, Menter D, Cavanaugh PG, Neagos G, Moilanen D, Taylor JD and Sloane BF. Acta Clin. Belg. 38: 53–67, 1983.

    PubMed  CAS  Google Scholar 

  85. Fitzpatrick F, Bundy G, Gorman R, Honohan T, McGuire J and Sun F. Biochim. Biophys. Acta 573: 238–244, 1979.

    PubMed  CAS  Google Scholar 

  86. Hara Y, Steiner M and Baldini MS. Cancer Res. 40: 1217–1222, 1980.

    PubMed  CAS  Google Scholar 

  87. Honn KV, Menter DG, Onoda JM, Taylor JD and Sloane BF. In: Cancer Invasion and Metastasis: Biologic and Therapeutic Aspects (Eds. Nicolson GL and Milas L), Raven Press:New York, pp. 361–368, 1984.

    Google Scholar 

  88. Diglio CA, Grammas P, Giacomelli F and Weiner J. Lab. Invest. 46: 544–563, 1982.

    Google Scholar 

  89. George JW, Thoi LL and Morgan RK. Thromb. Res. 23: 69–77, 1981.

    Article  PubMed  CAS  Google Scholar 

  90. Thompson CB, Eaton K, Princiotta SM, Rushin CA and Valleri CR. Br. J. Haematol. 50: 509–519, 1982.

    Article  PubMed  CAS  Google Scholar 

  91. Fantone JC, Elgas LJ, Weinberger L and Varani J. Oncology 40: 421–426, 1983.

    Article  PubMed  CAS  Google Scholar 

  92. Marcum JM, McGill M, Bastida E, Ordinas A and Jamieson GA. J. Lab. Clin. Med. 96: 1048–1053, 1980.

    Google Scholar 

  93. Stringfellow DA and Fitzpatrick FA. Nature (London) 282: 76–78, 1979.

    Article  CAS  Google Scholar 

  94. Willmott N, Malcolm A, McLeod T, Gracie A and Caiman KC. Invasion Metastasis 3: 32–51, 1983.

    PubMed  CAS  Google Scholar 

  95. Salmon JA, Smith IE, Flower RS, Moncada S and Vane JR. Biochim. Biophys. Acta 523: 250–262, 1978.

    PubMed  CAS  Google Scholar 

  96. Moncada S. Br. J. Pharmacol. 76: 3–31, 1982.

    PubMed  CAS  Google Scholar 

  97. Szczeklik A, Nizankowski R, Skawinski S, Szczeklik J, Gluszko P and Gryglewski RJ. Lancet 1: 1111–1114.

    Google Scholar 

  98. Szczeklik A, Gryglewski RJ, Nizankcwski R, Musial J, Pieton R and Mruk J. Pharmacol. Res. Commun. 10: 545–556, 1978.

    Article  PubMed  CAS  Google Scholar 

  99. Watkins WD, Peterson MB, Crone RK, Shannon DC and Levine L. Lancet 1: 1083, 1980.

    Article  PubMed  CAS  Google Scholar 

  100. Hall RJC and Dewar HA. Lancet 1: 949, 1981.

    Article  PubMed  CAS  Google Scholar 

  101. Morton DR and Brokow FC. J. Org. Chem. 44: 2880–2887, 1979.

    Article  CAS  Google Scholar 

  102. Nishiyama H and Ohno K. Tetrahed. Lett. 36: 3481–3484, 1979.

    Article  Google Scholar 

  103. Whittle BJR, Mancada S, Whiting F and Vane JR. Prostaglandins 19: 605–627, 1980.

    Article  PubMed  CAS  Google Scholar 

  104. Pike JE and Bundy GL. In: Prostaglandins and Cancer (Eds. Powles TJ, Bockman RS, Honn KV and Ramwell P), Alan R. Liss:New York, pp. 67–77, 1982.

    Google Scholar 

  105. Seuter F, Basse WD, Mang F, Hoffmeister F, Moller E and Horstmann H. Arzneim.-Forsch./Drug Res. 29: 54–59, 1979.

    CAS  Google Scholar 

  106. Buchanan MR, Blajchman M and Hirsch J. Thromb. Res. 28: 157–170, 1982.

    Article  PubMed  CAS  Google Scholar 

  107. Fiedler VB. Basic Res. Cardiol. 78: 266–280, 1983.

    Article  PubMed  CAS  Google Scholar 

  108. Fiedler VB. Eur. J. Pharmacol. 88: 263–267, 1983.

    Article  PubMed  CAS  Google Scholar 

  109. Philipp E, Ritter W and Patzschke K. Thromb. Res. Suppl. 4: 129–133, 1983.

    Article  PubMed  CAS  Google Scholar 

  110. Vermylen J, Chamone DAF and Verstraete M. Lancet 1: 518–520, 1979.

    Article  PubMed  CAS  Google Scholar 

  111. Carreras LO, Chamone DAF, Klerckx P and Vermylen J. Thromb. Res. 19: 663–670, 1980.

    Article  PubMed  CAS  Google Scholar 

  112. Chamone DAF, van Damme B, Carreras L0 and Vermylen J. Haemostasis 10: 297–303, 1979.

    Google Scholar 

  113. Eling TE, Honn KV, Busse WD, Seuter F and Marnett LJ. In: Prostaglandins and Cancer (Eds. Powles TJ, Bockman RS, Honn KV and Ramwell P), Alan R. Liss:New York, pp. 783–787, 1982.

    Google Scholar 

  114. Marnett LJ, Siedlik PH, Ochs R, Das M, Honn KV, Warnock R, Tainer B and Eling TE. Mbl. Pharmacol., in press.

    Google Scholar 

  115. Fischer S, Struppler M and Weber PC. Biochem. Riarmacol. 32: 2231–2236, 1983.

    Article  CAS  Google Scholar 

  116. Deckmyn H, van Houtte E, Verstraete M and Vermylen J. Biochem. Pharmacol. 32: 2757–2762, 1983.

    Article  PubMed  CAS  Google Scholar 

  117. Weksler BB, Ley LW and Jaffe EA. J. Clin. Invest. 62: 923–930, 1978.

    Article  PubMed  CAS  Google Scholar 

  118. Brotherton AFA, Macfarlane DE and Hoak JC. Thromb. Res. 28: 637–647, 1982.

    Article  PubMed  CAS  Google Scholar 

  119. Hemler ME, Cook HW and Lands WEM. Arch. Biochem. Biophys. 193: 340–345, 1979.

    Article  PubMed  CAS  Google Scholar 

  120. Hemler ME and Lands WEM. J. Biol. Chem. 255: 6253–6261, 1980.

    PubMed  CAS  Google Scholar 

  121. Kent RS, Diedrich SL and Whorton AR. J. Clin. Invest. 72: 455–465, 1983.

    Article  PubMed  CAS  Google Scholar 

  122. Brotherton AFA and Hoak JC. J. Clin. Invest. 72: 1255–1261, 1983.

    Article  PubMed  CAS  Google Scholar 

  123. Honn KV and Dunn JR. FEBS Lett. 139: 65–68, 1982.

    Article  PubMed  CAS  Google Scholar 

  124. Busse WD, Mardin M, Grutzmann R, Dunn JR, Theodoreau M, Sloane BF and Honn KV. Fed. Proc. Fed. Am. Soc. Exp. Biol. 41: 1717, 1982.

    Google Scholar 

  125. Herman AG, Claeys M, Moncada S and Vane JR. Prostaglandins 18: 439–452, 1979.

    Article  PubMed  CAS  Google Scholar 

  126. Sevilla MD and Marnett LJ. Biochem. Biophys. Res. Commun. 115: 800–806, 1983.

    Article  PubMed  CAS  Google Scholar 

  127. Wong PY-K, Chao P H-W and McGiff JC. J. Pharmacol. Exp. Ther. 223: 757–760, 1982.

    PubMed  CAS  Google Scholar 

  128. Machleidt C, Forstermann U, Anhut H and Hertting G. Eur. J. Pharmacol. 74: 19–26, 1981.

    Article  PubMed  CAS  Google Scholar 

  129. Rosenkranz B, Fischer C, Weimer KE and Frolich JC. J. Biol. Chem. 255: 10194–10198, 1980.

    PubMed  CAS  Google Scholar 

  130. Ambrus JL, Ambrus IM, Gastpar H and Williams C. J. Med. 13: 35–47, 1982.

    PubMed  CAS  Google Scholar 

  131. Hall ER, Chen YC, Ho T and Wu KK. Thromb. Res. 27: 501–511, 1982.

    Article  PubMed  CAS  Google Scholar 

  132. Bertele V, Falanga A, Roncaglioni MC, Cerletti C and de Gaetano G. Thronb. Haemostasis 47: 294, 1982.

    CAS  Google Scholar 

  133. Aiken JW, Shebuski RJ, Miller OV and Gorman RR. J. Pharmacol. Exp. Ther. 219: 299–308, 1981.

    CAS  Google Scholar 

  134. Defreyn G, Deckmyn H and Vermylen J. Thromb. Res. 26: 389–400, 1982.

    Article  PubMed  CAS  Google Scholar 

  135. Gryglewski RJ, Bunting S, Moncada S, Flower RJ and Vane JR. Prostaglandins 12: 685–713, 1976.

    Article  PubMed  CAS  Google Scholar 

  136. Needleman P, Wyche A and Raz A. J. Clin. Invest. 63: 345–349, 1979.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. Kenneth V. Honn
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. James M. Onoda
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. David G. Menter
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. John D. Taylor
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Bonnie F. Sloane
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Wayne State University, 210 Science Hall, Detroit, 48202, MI, USA

    Kenneth V. Honn

  2. Department of Pharmacology, Wayne State University, 540 East Canfield, Detroit, 48201, MI, USA

    Bonnie F. Sloane

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Martinus Nijhoff Publishing, Boston

About this chapter

Cite this chapter

Honn, K.V., Onoda, J.M., Menter, D.G., Taylor, J.D., Sloane, B.F. (1984). Prostacyclin/Thromboxanes and Tumor Cell Metastasis. In: Honn, K.V., Sloane, B.F. (eds) Hemostatic Mechanisms and Metastasis. Developments in Oncology, vol 22. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3831-4_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-3831-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3833-8

  • Online ISBN: 978-1-4613-3831-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation