Advertisement

Steroid Treatment of Acute Myocardial Infarction: Some Implications for Clinical Trials in General

  • P. L. Dern
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 41)

Abstract

Glucocorticoid studies of infarct size illustrate features of more general interest for clinical trials. A point of note is the close relationship of studies in animals to those in humans.

Keywords

Myocardial Infarction Acute Myocardial Infarction Infarct Size Reduce Infarct Size Myocardial Infarct Size 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Libby P, Maroko PR, Bloor CH, Sobel BE, Braunwald E: Reduction of experimental myocardial infarct size by corticosteroid administration. J Clin Invest. 52: 599–606, 1973.PubMedCrossRefGoogle Scholar
  2. 2.
    Morrison J, Reduto L, Pizzarello R, Geller K, Maley T, Gullota S: Modification of myocardial injury in man by corticosteroid administration. Circulation 51: I200–203, 1976.Google Scholar
  3. 3.
    Roberts R, de Melli V, Sobel BE: Deleterious effects of methylprednisolone in patients with myocardial infarction. Circulation 53: I204–206, 1976.PubMedGoogle Scholar
  4. 4.
    Bulkley BH, Roberts WC: Steroid therapy during acute myocardial infarction. Am J Med 56: 244–250, 1974.PubMedCrossRefGoogle Scholar
  5. 5.
    Green RM, Cohen J, DeWeese JA: Short-term use of corticoids after experimental myocardial infarction: effects on ventricular function and infarct healing. Circulation 50: I101–103, 1974.Google Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1984

Authors and Affiliations

  • P. L. Dern

There are no affiliations available

Personalised recommendations