Abstract
The presence of abnormal kidney function predisposes affected individuals to adverse effect from drugs (1–3). Persons with kidney disease receive drugs for the same variety of day to day elective or emergency medical problems as do other persons in the general population. In addition, those with advanced renal disease receive drugs for the management of complications of the renal failure. Persons with systemic diseases associated with significant kidney involvement frequently require drug treatment for a variety of extrarenal medical and/or surgical problems. Finally, individuals developing acute renal failure are often receiving or are about to receive, one or more drugs in the course of treatment of the precipitating illness. Thus, clinicians are frequently involved with the use of many different drugs in patients with varying degrees of renal dysfunction, where the potential for adverse drug-disease interactions is formidable.
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Briggs, W.A., McDonald, F.D., Sillix, D.M., MacDougall, M.L. (1984). Use of Drugs in Uremia and Dialysis. In: Suki, W.N., Massry, S.G. (eds) Therapy of Renal Diseases and Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3807-9_41
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DOI: https://doi.org/10.1007/978-1-4613-3807-9_41
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