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Inhibition of Metabolic Cooperation Between Cultured Mammalian Cells by Selected Tumor Promoters, Chemical Carcinogens, and Other Compounds

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Application of Biological Markers to Carcinogen Testing

Part of the book series: Environmental Science Research ((ESRH,volume 29))

Abstract

Inhibition of metabolic cooperation between cells may result in tumor promotion or teratogenesis. Using a cell culture assay designed to measure such inhibition as a function of mutant cell recovery in reconstruction experiments with cocultivated mutant (HGPRT-) and wild-type (HGPRT+) cells, we tested several chemicals for their ability to inhibit metabolic cooperation.

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© 1983 Plenum Press, New York

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Malcolm, A.R., Mills, L.J., McKenna, E.J. (1983). Inhibition of Metabolic Cooperation Between Cultured Mammalian Cells by Selected Tumor Promoters, Chemical Carcinogens, and Other Compounds. In: Milman, H.A., Sell, S. (eds) Application of Biological Markers to Carcinogen Testing. Environmental Science Research, vol 29. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3790-4_43

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  • DOI: https://doi.org/10.1007/978-1-4613-3790-4_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3792-8

  • Online ISBN: 978-1-4613-3790-4

  • eBook Packages: Springer Book Archive

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