Skip to main content

Modified Polysaccharides with Potential Anti-Arrhythmic Activity

  • Chapter
Modification of Polymers

Part of the book series: Polymer Science and Technology ((POLS,volume 21))

Abstract

The chemical combination of pharmacologically active compounds with polymers is currently receiving considerable attention. Objectives are to improve the duration of activity, to obtain a more cell-specific uptake or to reduce the toxicity of the parent drug1,2,3 Macromolecular derivatives of a drug can be obtained either by converting the drug into a reactive derivative that can be polymerized or by binding the drug onto an existing natural or synthetic polymer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. S.W. Kim, R.V. Petersen and J. Feyen, “Drug Design,” Academic Press, New York, 1980, pg. 193.

    Google Scholar 

  2. H.G. Batz, Adv. in Polymer Sei., 23, 26 (1971).

    Google Scholar 

  3. H. Ringsdorf, J. Polymer Sei., Symp. 51, 135 (1975).

    Article  Google Scholar 

  4. L. Molteni, “Drug Carriers in Biologie and Medicine” (G. Gregoriadis, Ed.), Academic Press, New York, 1979, Chpt. 6.

    Google Scholar 

  5. M.I. Shtil’man, Russ. Chem. Rev., 48, 11 (1979).

    Google Scholar 

  6. A.D. Virnik, K.P. Khomyakov and I.F. Skokova, Russ. Chem. Rev., 44(7), 588 (1975).

    Article  ADS  Google Scholar 

  7. A. Jeanes, W.C. Haynes, C.A. William, I.C. Rankin, E.H. Melvin, M.J. Austin, J.E. Cluskey, B.E. Fisher, H.N. Tsuchiya and C.E. Rist, J. Am. Chem. Soc., 76, 5041 (1954).

    Article  Google Scholar 

  8. K.P. Khomyakov, M.A. Penenzhik, A.D. Virnik and Z.A. Rogovin, Vysokomol. Soyed., 7(6), 1030 (1965).

    Google Scholar 

  9. B. Lindberg and S. Svensson, Acta Chem. Scand., 22, 1907 (1968).

    Article  Google Scholar 

  10. E. Pacsu, Text. Res. J., 16, 105 (1956).

    Article  Google Scholar 

  11. Z.A. Rogovin, A.D. Virnik, K.P. Khomyakov, O.P. Laletina and M.A. Penenzhik, J. Macromol. Sei.-Chem., A6(3), 569 (1972).

    Article  Google Scholar 

  12. M.F. Ishak and T. Painter, Acta Chem. Scand., 25, 3875 (1971).

    Article  Google Scholar 

  13. T. Painter and B. Larsen, Acta Chem. Scand., 24, 813 (1970).

    Article  Google Scholar 

  14. T. Painter and B. Larsen, Acta Chem. Scand., 24, 2366 (1970).

    Article  Google Scholar 

  15. T. Painter and B. Larsen, Acta Chem. Scand., 27, 1957 (1973).

    Article  Google Scholar 

  16. K.P. Khomyakov, A.D. Virnik, S.N. Ushakov and Z.A. Rogovin, Vysokomol. Soyed., 7(6), 1035 (1965).

    Google Scholar 

  17. L.S. Levitt, J. Org. Chem., 20, 1297 (1955).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Plenum Press, New York

About this chapter

Cite this chapter

Schacht, E., Ruys, L., Vermeersch, J., Goethals, E. (1983). Modified Polysaccharides with Potential Anti-Arrhythmic Activity. In: Carraher, C.E., Moore, J.A. (eds) Modification of Polymers. Polymer Science and Technology, vol 21. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3748-5_22

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-3748-5_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3750-8

  • Online ISBN: 978-1-4613-3748-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics