Abstract
The heterozygous and homozygous effects of mutations recovered from a biochemical screen of mouse samples are described. Of the total of 28 electrophoretically detected mutations only one, a Pgm-2 mobility mutation appears to have caused a change to a previously known allelic form. All but one electrophoretically detected allele have been shown to be homozygous viable. Two mutations identified by other means are homozygous lethal; the first is a mutant detected because of its reduced PK-3 activity in heterozygotes, and the second is a morphologically detected mutation at the d locus. Three dominant visible mutations are also described briefly.
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© 1983 Plenum Press, New York
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Lewis, S.E., Johnson, F.M. (1983). Dominant and Recessive Effects of Electrophoretically Detected Specific Locus Mutations. In: de Serres, F.J., Sheridan, W. (eds) Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. Environmental Science Research, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3739-3_17
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DOI: https://doi.org/10.1007/978-1-4613-3739-3_17
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