Abstract
Accurate evaluation of genetic risk requires a good understanding of the mechanism. This report illustrates this point by demonstrating how factors such as repair, germ cell stage, stock of mice and processes that take place after fertiliztion affect the induction of chromosomal aberrations from both qualitative and quantitative standpoints.
Research sponsored by the Office of Health and Environmental Research, U.S. Department of Energy, under contract W-7405-eng-26 with the Union Carbide Corporation.
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© 1983 Plenum Press, New York
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Generoso, W.M., Cain, K.T., Bandy, A.J. (1983). Some Factors Affecting the Mutagenic Response of Mouse Germ Cells to Chemicals. In: de Serres, F.J., Sheridan, W. (eds) Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. Environmental Science Research, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3739-3_14
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DOI: https://doi.org/10.1007/978-1-4613-3739-3_14
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