Abstract
Atherosclerosis or better said atherothrombosis is the pathological basis for coronary heart disease (C.R.D.). Autopsy studies have shown a correlation between the prevalence of atherothrombotic complicated lesions and coronary mortality at the population level. On the other hand correlations between complicated lesions and the major coronary risk factors like hypercholesterolemia, high blood pressure or smoking have also been observed.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
G. Rose, P. J. S. Hamilton, H. Keen, D. D. Reid, P. MacCartney, R. J. Jarrett, Myocardial ischaemia, risk factors and death from coronary heart disease, Lancet, i:105 (1977).
A. M. Telford, C. Wilson, Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome, Lancet, i:1225 (1981).
A. Keys, Seven Countries, A multivariate Analysis of Death and Coronary Heart Disease, Harvard University Press, Cambridge, Massachusetts and London, England (1980).
The Multiple Risk Factor Intervention (MRFIT), A national study of primary prevention of coronary heart disease, JAMA., 235: 825 (1976).
I. Hjermann, K. V. Byre, I. Holme, P. Leren, Effect of diet and smoking intervention on the incidence of coronary heart disease, Lancet, ii:1303 (1981).
J. T. Salonen, P. Puska, H. Mustaniemi, Changes in morbidity and mortality during comprehensive community programme to control cardiovascular diseases during 1972–7 in North Karelia, Brit. Med. J., 2: 1178 (1979).
M. Kornitzer, G. de Backer, M. Dramaix, C. Thilly, The Belgian Heart Disease Prevention Project: Modification of the Coronary risk profile in an industrial population, Circulation, 61:18 (1980).
European Society of Cardiology, Preventing Coronary Heart Disease; A guide for the practising physician, Van Gorcum Assen, The Netherlands (1978).
G. Christakis, S. H. Rinzler, M. Archer, A. Kraus, Effect of the anti‐coronary club program on coronary heart disease: risk factor status, JAMA., 198:129 (1966).
S. Dayton, Rationale for use of lipid-lowering drugs, Federation Proceedings, 30:849 (1971).
I. D. Frantz, E. A. Dawson, K. Kuba, E. R. Brewer, L. C. Gatewood, G. E. Bartsch, The Minnesota Coronary Survey: effect of diet on cardiovascular events and deaths (Abstract), Circulation, 51 and 52, suppl. II, p. 4 (1975).
O. Turpeinen, M. Miettinen, M. J. Karvonen, P. Roine, M. Pekkarinen, E. J. Lehtosuo, P. Alivirta, Dietary prevention of coronary heart disease: long-term experiment. I. Observations on male subjects, Am. J. Clin. Nutr., 21:255 (1968).
M. F. Oliver, J. A. Heady, J. N. Morris, J. Cooper, A cooperative trial in the primary prevention of ischaemic heart disease using clofibrate, Brit. Heart J., 40:1069 (1978).
M. F. Oliver, J. A. Heady, J. N. Morris, J. Cooper, W.H.O. Cooperative trial on primary prevention of ischaemic heart disease using clofibrate to lower serum cholesterol: Mortality follow-up, Lancet, ii:379 (1980).
M. F. Oliver, Cholesterol, coronaries, clofibrate and death, N. Engl. J. Med., 299:1360 (1978).
G. Rose, P. J. S. Hamilton, L. Colwell, M. J. Shipley, A randomized controlled trial of anti-smoking advice: 10 year results, J. Epidem. Com. Hlth., 36:102 (1982).
Veterans Administration Cooperative Study Group on Antihypertensive Agents, Effects of treatment on morbidity in hypertension: I. Results in patients with diastolic blood pressure averaging 115 through l29mmHg, JAMA., 201:1028 (1967).
Veterans Administration Cooperative Study Group on Antihypertensive Agents, Effects of treatment on morbidity in hypertension: II. Results in patients with diastolic blood pressure averaging 90 through l14mmHg, JAMA., 213:1143 (1970).
W. McFate Smith, Treatment of mild hypertension: Results of aten-year intervention trial, Circ. Res., 40 Supple I., 98 (1977).
The Australian Therapeutic Trial in Mild Hypertension, Report by the Management Committee, Lancet, i:126l (1980).
Hypertension Detection and Follow‐up Program Cooperative Group, Five‐year findings of the hypertension detection and followup program: I. Reduction in mortality of persons with high blood pressure, including mild hypertension, JAMA., 242:2562 (1979).
A. Helgeland, Treatment of mild hypertension: a five year controlled drug trial, The Oslo Study, Am. J. Med., 5:725 (1980).
J. Tuomilehto, The most recent lesson from community control of cardiovascular diseases, Acta Cardiol., 35:251 (1980).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Plenum Press, New York
About this chapter
Cite this chapter
Kornitzer, M. (1983). Primary Prevention of Coronary Heart Disease. In: Raineri, A., Kellermann, J.J. (eds) Selected Topics in Preventive Cardiology. Ettore Majorana International Science Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3736-2_3
Download citation
DOI: https://doi.org/10.1007/978-1-4613-3736-2_3
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-3738-6
Online ISBN: 978-1-4613-3736-2
eBook Packages: Springer Book Archive