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Chemically Induced Changes in Sperm in Animals and Humans

  • John C. Topham

Abstract

Semen assays provide effective methods for the evaluation of induced damage to mammalian germ cells. Increases in the number of abnormally shaped sperm or decreases in sperm count or motility are associated with reduced fertility in humans and animals. In 1978, Wyrobek and Bruce(1) reviewed the methods and results obtained with the F0 sperm head morphology assay in mice, discussed some examples of chemicals that induced abnormal sperm morphology in humans, and described the rationale for both the F0 and F1 sperm head morphology assays in mice.

Keywords

Sperm Count Lead Acetate Human Sperm Semen Quality Sperm Head 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • John C. Topham
    • 1
  1. 1.Pharmaceuticals Division, Safety of MedicinesImperial Chemical Industries PLCMacclesfield, CheshireUK

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