Abstract
Hundreds of compounds have now been tested for mutagenic activity in many laboratories throughout the world. Mutagenicity tests are performed to validate a variety of assay systems and to contribute to the toxicological safety evaluation of chemicals. An area of research in genetic toxicology that has important implications for the development of safe chemical products is the study of series of homologous compounds in order to relate chemical structure to genetic activity.
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Shahin, M.M., Bugaut, A., Kalopissis, G. (1983). Relationships between the Chemical Structure and Mutagenic Activity of Monocyclic Aromatic Amines. In: de Serres, F.J. (eds) Chemical Mutagens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3694-5_5
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