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Photoallergy

  • Warwick L. Morison
  • Irene E. Kochevar

Abstract

Photoallergy is a state of specifically altered reactivity towards an exogenous chemical in which photons play some role. The usual manifestation is an eczematous rash that occurs after the skin is exposed to both an offending chemical and electromagnetic radiation. In many conditions classified as photoallergic, the evidence for an immune mechanism is suggestive, not conclusive. Immunologic reactivity in photoallergy is thought to be directed toward an antigen that arises as the result of a reaction(s) initiated by the absorption of radiation by (1) the chemical or a complex containing the chemical, (2) a biotransformation product of the chemical, or (3) a host molecule altered by the chemical.

Keywords

Contact Dermatitis Action Spectrum Contact Allergy Minimal Erythemal Dose Photo Sensitizer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Warwick L. Morison
    • 1
  • Irene E. Kochevar
    • 2
  1. 1.Basic Research Program-LBIFrederick Cancer Research FacilityFrederickUSA
  2. 2.Department of Dermatology, Harvard Medical SchoolMassachusetts General HospitalBostonUSA

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