Safety Precautions for the Handling of TCDD

Part of the Environmental Science Research book series (ESRH, volume 26)


During the past 80 years there have been numerous reports on a severe form of acne and related symptoms associated with exposure to TCDD and/or structurally similar aromatic chlorine compounds. Many of these reports dealt with the exposure of laboratory staff and workers in the chemical industry. The need thus arises to prescribe particularly stringent safety precautions for laboratory experiments with these extremely toxic substances. At the same time a critical evaluation of the necessity of these experiments should be carried out.

In 1976, a list of safety precautions for the handling of TCDD were prepared by the Federal Health Office; these are presented in detail. Numerous technical details as well as possibilities for improvisation are discussed. Moreover, simple solutions for the safe disposal of contaminated solids and liquids are described. Finally, the necessity of medical check-ups for laboratory staff who handle these compounds is emphasized.


Activate Carbon Related Symptom Laboratory Staff Safety Precaution Cyclic Ether 
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  1. Crosby, D. G., Wong, A. S., Plimmer, J. R., and Woolson, E. A., 1974, Photodecomposition of chlorinated dibenzo-p-dioxins, Science., 173: 748–749, 1971.CrossRefADSGoogle Scholar
  2. Herxheimer, K., 1899, Uber Chlorakne, Munch. Med. Woch, 46.1:278.Google Scholar
  3. Kimmig, J. and Schulz, K. H., 1957, Occupational acne (so-called chloracne) due to chlorinated aromatic cyclic ethers, Dermatologia, 115 (4): 540–546.CrossRefGoogle Scholar
  4. Oliver, R. M., 1975, Toxic effects of 2,3,7,8-tetrachlorodibenzo- 1,4-dioxin in laboratory workers, Brit. J. Ind. Med., 32(1):49–53.MathSciNetGoogle Scholar
  5. Plimmer, J. R., Klingebiel, U. I., Crosby, D. G., and Wong, A. S. 1973, Photochemistry of dibenzo-p-dioxins, Adv. Chem. Ser., 120: 44–54.CrossRefGoogle Scholar
  6. Sandermann, W., Stockmann, H., and Casten, R., 1957, Uber die pyrolyse des pentachlorphenols, Chem. Ber., 90–690–692.CrossRefGoogle Scholar
  7. Stehl, R. H., Papenfuss, R. R., Bredeweg, R. A., and Roberts, P. W., 1973, The stability of pentachlorophenol and chlorinated dioxins to sunlight, heat and combustion, Adv. Chem Ser. 120:119–125.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • H. Beck
    • 1
  1. 1.Bundesgesundheitsamt (Federal Health Office)BerlinFederal Republic of Germany

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