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Mutagenic and Oncogenic Effects of Chloromethanes, Chloroethanes and Halogenated Analogues of Vinyl Chloride

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Genotoxic Effects of Airborne Agents

Part of the book series: Environmental Science Research ((ESRH,volume 25))

Abstract

In the early 1970’s, information bearing on the mutagenicity and carcinogenicity if vinyl chloride (VC) in experimental test systems and in humans came to the attention of the public health community. As a result, emphasis was placed on the evaluation of potential genotoxic and carcinogenic effects of a number of halogenated hydrocarbons structurally related to VC. This response was of particular concern as many of these substances are in high volume production and have a large number of individuals exposed in the occupational setting. As a result of pollution from industrial effluents, many of these substances have been identified in community water supplies. Some of these substances also have been or still are contained in consumer products.

The views expressed do not necessarily represent those of the Occupational Safety and Health Administration.

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Author information

Authors and Affiliations

  1. Office of Carcinogen Identification and Classification, Health Standards Program, 200 Constitution Avenue, N. W., Washington, D.C., 20210, USA

    Peter F. Infante & Theodora A. Tsongas

  2. Department of Labor, Occupational Safety and Health Administration, 200 Constitution Avenue, N. W, Washington, D.C., 20210, USA

    Peter F. Infante & Theodora A. Tsongas

Authors
  1. Peter F. Infante
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  2. Theodora A. Tsongas
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Editors and Affiliations

  1. Brookhaven National Laboratory, New York, Upton, USA

    Raymund R. Tice , Daniel L. Costa  & Karen M. Schaich ,  & 

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© 1982 Plenum Press, New York

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Infante, P.F., Tsongas, T.A. (1982). Mutagenic and Oncogenic Effects of Chloromethanes, Chloroethanes and Halogenated Analogues of Vinyl Chloride. In: Tice, R.R., Costa, D.L., Schaich, K.M. (eds) Genotoxic Effects of Airborne Agents. Environmental Science Research, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3455-2_23

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  • DOI: https://doi.org/10.1007/978-1-4613-3455-2_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3457-6

  • Online ISBN: 978-1-4613-3455-2

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