Mutagenic and Oncogenic Effects of Chloromethanes, Chloroethanes and Halogenated Analogues of Vinyl Chloride

  • Peter F. Infante
  • Theodora A. Tsongas
Part of the Environmental Science Research book series (ESRH, volume 25)


In the early 1970’s, information bearing on the mutagenicity and carcinogenicity if vinyl chloride (VC) in experimental test systems and in humans came to the attention of the public health community. As a result, emphasis was placed on the evaluation of potential genotoxic and carcinogenic effects of a number of halogenated hydrocarbons structurally related to VC. This response was of particular concern as many of these substances are in high volume production and have a large number of individuals exposed in the occupational setting. As a result of pollution from industrial effluents, many of these substances have been identified in community water supplies. Some of these substances also have been or still are contained in consumer products.


Vinyl Chloride Technical Report Series Tetraethyl Lead Ethylene Dibromide Ethylene Dichloride 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Peter F. Infante
    • 1
    • 2
  • Theodora A. Tsongas
    • 1
    • 2
  1. 1.Office of Carcinogen Identification and ClassificationHealth Standards ProgramN. W.USA
  2. 2.Department of LaborOccupational Safety and Health AdministrationUSA

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