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Benzene Metabolites: Evidence for an Epigenetic Mechanism of Toxicity

  • Chapter
Genotoxic Effects of Airborne Agents

Part of the book series: Environmental Science Research ((ESRH,volume 25))

Abstract

Benzene is the most widely recognized chemical of industrial importance which is associated with toxicity to the blood and blood forming organs. Occupational exposure produces a variety of blood dyscrasias ranging from transient leukopenia or lymphocytopenia to aplastic anemia (1,2). In recent years interest has focused on the association of chronic benzene exposure with increased risk of leukemia (3–5) or lymphoma (6–8).

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Authors and Affiliations

  1. Chemical Industry Institute of Toxicology, P.O. Box 12137, Research Triangle Park, NC, 27709, USA

    R. D. Irons & R. W. Pfeifer

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  1. R. D. Irons
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  2. R. W. Pfeifer
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Editors and Affiliations

  1. Brookhaven National Laboratory, New York, Upton, USA

    Raymund R. Tice , Daniel L. Costa  & Karen M. Schaich ,  & 

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© 1982 Plenum Press, New York

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Irons, R.D., Pfeifer, R.W. (1982). Benzene Metabolites: Evidence for an Epigenetic Mechanism of Toxicity. In: Tice, R.R., Costa, D.L., Schaich, K.M. (eds) Genotoxic Effects of Airborne Agents. Environmental Science Research, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3455-2_19

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  • DOI: https://doi.org/10.1007/978-1-4613-3455-2_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3457-6

  • Online ISBN: 978-1-4613-3455-2

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